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2.A.7.12.14
Probable UDP-sugar transporter protein SLC35A5 (Solute carrier family 35 member A5)

Accession Number:Q9BS91
Protein Name:Probable UDP-sugar transporter protein SLC35A5
Length:424
Molecular Weight:48500.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate UDP-sugar

Cross database links:

Genevestigator: Q9BS91
eggNOG: COG0697
HEGENOM: HOG000154236
Entrez Gene ID: 55032   
Pfam: PF04142   
KEGG: hsa:55032   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0005338 F:nucleotide-sugar transmembrane transporter activity
GO:0005351 F:sugar:hydrogen symporter activity

References (5)

[1] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[5] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEKQCCSHPV ICSLSTMYTF LLGAIFIALS SSRILLVKYS ANEENKYDYL PTTVNVCSEL 
61:	VKLVFCVLVS FCVIKKDHQS RNLKYASWKE FSDFMKWSIP AFLYFLDNLI VFYVLSYLQP 
121:	AMAVIFSNFS IITTALLFRI VLKRRLNWIQ WASLLTLFLS IVALTAGTKT LQHNLAGRGF 
181:	HHDAFFSPSN SCLLFRSECP RKDNCTAKEW TFPEAKWNTT ARVFSHIRLG MGHVLIIVQC 
241:	FISSMANIYN EKILKEGNQL TESIFIQNSK LYFFGILFNG LTLGLQRSNR DQIKNCGFFY 
301:	GHSAFSVALI FVTAFQGLSV AFILKFLDNM FHVLMAQVTT VIITTVSVLV FDFRPSLEFF 
361:	LEAPSVLLSI FIYNASKPQV PEYAPRQERI RDLSGNLWER SSGDGEELER LTKPKSDESD 
421:	EDTF