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2.A.7.12.7
Golgi UDP-N-acetylglucosamine transporter (Ishida et al., 1999a). Conserved Glu-47 and Lys-50 residues are critical for UDP-N-acetylglucosamine/UMP antiport activity of the mouse Golgi-associated transporter (Toscanini et al. 2019).

Accession Number:Q9Y2D2
Protein Name:UDP-N-acetylglucosamine transporter
Length:325
Molecular Weight:35985.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate UDP-N-acetylglucosamine

Cross database links:

Genevestigator: Q9Y2D2 Q9Y2D2
eggNOG: prNOG10084 COG0697
HEGENOM: HBG608296 HOG000216649
RefSeq: NP_036375.1   
Entrez Gene ID: 23443   
Pfam: PF04142   
OMIM: 605632  gene
KEGG: hsa:23443    hsa:23443   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0005351 F:sugar:hydrogen symporter activity
GO:0005462 F:UDP-N-acetylglucosamine transmembrane trans...
GO:0006047 P:UDP-N-acetylglucosamine metabolic process
GO:0015788 P:UDP-N-acetylglucosamine transport
GO:0005462 F:UDP-N-acetylglucosamine transmembrane transporter activity

References (6)

[1] “Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter.”  Ishida N.et.al.   10393322
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[4] “Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter.”  Ishida N.et.al.   10393322
[5] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[6] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFANLKYVSL GILVFQTTSL VLTMRYSRTL KEEGPRYLSS TAVVVAELLK IMACILLVYK 
61:	DSKCSLRALN RVLHDEILNK PMETLKLAIP SGIYTLQNNL LYVALSNLDA ATYQVTYQLK 
121:	ILTTALFSVS MLSKKLGVYQ WLSLVILMTG VAFVQWPSDS QLDSKELSAG SQFVGLMAVL 
181:	TACFSSGFAG VYFEKILKET KQSVWIRNIQ LGFFGSIFGL MGVYIYDGEL VSKNGFFQGY 
241:	NRLTWIVVVL QALGGLVIAA VIKYADNILK GFATSLSIIL STLISYFWLQ DFVPTSVFFL 
301:	GAILVITATF LYGYDPKPAG NPTKA