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2.A.7.12.8
UDP-galactose transporter, UGT (Had-1) (Ishida et al., 1999b)

Accession Number:Q9R0M8
Protein Name:UDP-galactose translocator aka Had1
Length:390
Molecular Weight:40766.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate UDP-galactose

Cross database links:

Genevestigator: Q9R0M8
RefSeq: NP_001077406.1   
Entrez Gene ID: 22232   
Pfam: PF04142   
KEGG: mmu:22232   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0005351 F:sugar:hydrogen symporter activity
GO:0005459 F:UDP-galactose transmembrane transporter act...
GO:0015780 P:nucleotide-sugar transport

References (2)

[1] “Indispensability of transmembrane domains of Golgi UDP-galactose transporter as revealed by analysis of genetic defects in UDP-galactose transporter-deficient murine had-1 mutant cell lines and construction of deletion mutants.”  Ishida N.et.al.   10578063
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MAAVGVGGST AAAGAGAVSS GALEPGSTTA AHRRLKYISL AVLVVQNASL ILSIRYARTL 
61:	PGDRFFATTA VVMAEVLKGL TCLLLLFAQK RGNVKHLVLF LHEAVLVQYV DTLKLAVPSL 
121:	IYTLQNNLQY VAISNLPAAT FQVTYQLKIL TTALFSVLML NRSLSRLQWA SLLLLFTGVA 
181:	IVQAQQAGGS GPRPLDQNPG AGLAAVVASC LSSGFAGVYF EKILKGSSGS VWLRNLQLGL 
241:	FGTALGLVGL WWAEGTAVAS QGFFFGYTPA VWGVVLNQAF GGLLVAVVVK YADNILKGFA 
301:	TSLSIVLSTV ASIRLFGFHL DPLFALGAGL VIGAVYLYSL PRGAVKAIAS ASASGPCIHQ 
361:	QPPGQPPPPQ LSSRGDLTTE PFLPKSVLVK