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2.A.7.13.6
Golgi GDP-mannose transporter of 397 aas and 10 TMSs, Gmt1.  Necessary for capsular biosynthesis, protein gycosylation and virulence (Wang et al. 2014).

Accession Number:P0CS02
Protein Name:GDP-mannose transporter 1
Length:397
Molecular Weight:42883.00
Species:Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) [214684]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate GDP-mannose

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSKPFVPTPN ISRPATPSSL DYGKDEASST LLRDMGERGD RERKDREERD KKEAMPSGQD 
61:	QVLPILSYCA ASIMMTVVNK YVVSGANFTM TFLLLAIQSS VCVLAVTTVK KLGFISFRDF 
121:	DKNDAKAWWP ISTLLVAVIY TGSKALQFLS IPVYTIFKNL TIILIAYGEV FMFNGAVSGL 
181:	TLCSFALMVG SSIIAAWSDI TSVWNKEPEL DPITGLEITV GPVSTIGGLN AGYIWMALNC 
241:	FVSAAYVLFM RKRIKVTGFK DWDSMYYNNL LSIPILVVFS LVIEDWGSES LALNFPASNR 
301:	VLLLSAMAFS GAAAVFISYS TAWCVRITGS TTYSMVGALN KLPVAASGIL FFGDPANFGN 
361:	ISAIAVGGVA GVVYAVAKTN QAKVEKARQA RAAGGRP