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2.A.7.14.2
Probable purine permease 18 (AtPUP18)

Accession Number:Q9C508
Protein Name:Probable purine permease 18
Length:390
Molecular Weight:44182.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Purines

Cross database links:

Genevestigator: Q9C508
eggNOG: NOG248976
HEGENOM: HOG000115800
Entrez Gene ID: 842166   
Pfam: PF03151   
KEGG: ath:AT1G57990   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005345 F:purine base transmembrane transporter activity

References (8)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis.”  Gillissen B.et.al.   10662864
[4] “Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database.”  Nuehse T.S.et.al.   15308754
[5] “Novel subsets of the Arabidopsis plasmalemma phosphoproteome identify phosphorylation sites in secondary active transporters.”  Hem S.et.al.   17869214
[6] “Temporal analysis of sucrose-induced phosphorylation changes in plasma membrane proteins of Arabidopsis.”  Niittylae T.et.al.   17586839
[7] “Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis thaliana.”  Jones A.M.E.et.al.   19245862
[8] “Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.”  Reiland S.et.al.   19376835

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEMTEASKQT TAEGSANPEP DQILSPRRSL ELKQKKWWIS VSLCIFLVLL GDSLVMLLLN 
61:	FFYVQDNRED SDQDLQYRGT WLQALVQNAA FPLLIPLFFI FPSPKQNQET TNTRFLSFRL 
121:	ILLYISLGVL VAAHSKLFAL GKLYANFGVF TLISATQLIF TAIFAAIINR FKFTRWIILS 
181:	IIGSILIYVF GSPEFGGEPD ENEEFYSIQA WLTFAASVAF ALSLCLFQLC FEKVLVKTKR 
241:	YGNKKVFRMV IEMQICVSFV ATVVCLVGLF ASGENKELQG DSHRFKKGET YYVLSLIGLA 
301:	LSWQVWAVGL MGLVLYVSGV FGDVVHMCTS PLVALFVVLA FDFMDDEFSW PRIGTLIATV 
361:	VALGSYFYTL HKRNKKKMVE LYQTENNIDV