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2.A.7.18.1
The high-affinity choline uptake transporter, LicB

Accession Number:P14182
Protein Name:LicB
Length:292
Molecular Weight:32449.00
Species:Haemophilus influenzae [727]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Apical cell membrane1 / Multi-pass membrane protein2
Substrate Choline

Cross database links:

HEGENOM: HBG495151
RefSeq: NP_439687.1   
Entrez Gene ID: 950400   
Pfam: PF00892   
BioCyc: HINF71421:HI_1538-MONOMER   
KEGG: hin:HI1538   

Gene Ontology

GO:0016020 C:membrane

References (2)

[1] “The molecular mechanism of phase variation of H. influenzae lipopolysaccharide.”  Weiser J.N.et.al.   2479481
[2] “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.”  Fleischmann R.D.et.al.   7542800

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRGYLFGILS AVFWALSGLL YNELPLSEYT ALGKVISLLF LIDFCSLLVI GITLWRKSAV 
61:	DFQGVFWQPA LSGILGGPIG MSAYLLSIHY LTIYYAAPLS SLFPVFAALM SYWILKEKIT 
121:	KTAQFGFALA IISSSLLAIE VGQEITFNTI GFIFLIICIL GWSSEIVISS YTMRSLSGLQ 
181:	VYFLRLCGST IGYLLILFIL SLKNFSLDIL SFNYVQIAGV IIFGALSYCC YYQAIYLLKP 
241:	IKAMALNITY SVWAIGLGYL LYKQPIKPIT LLLTLLLSAG VIVTLYYKGE QK