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2.A.7.19.2
The uptake transporter for allantoin (Km = 50 μM) and other oxo derivatives of nitrogen heterocyclic compounds, UPS1 (ureide:H+ symport permease) (10 TMSs; 5 paralogues in Arabidopsis).  Also transports purine degradation products such as uric acid and xanthine but not adenine (Desimone et al., 2002).

Accession Number:Q9ZPR7
Protein Name:Ureide permease 1 aka UPS1
Length:390
Molecular Weight:42734.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Allantoin, Uric acid, Xanthine

Cross database links:

Genevestigator: Q9ZPR7
HEGENOM: HBG319274
RefSeq: NP_565303.1   
Entrez Gene ID: 814888   
KEGG: ath:AT2G03590   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005274 F:allantoin uptake transmembrane transporter ...
GO:0005524 F:ATP binding
GO:0015720 P:allantoin transport

References (2)

[1] “A novel superfamily of transporters for allantoin and other oxo derivatives of nitrogen heterocyclic compounds in Arabidopsis.”  Desimone M.et.al.   11971139
[2] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.”  Lin X.et.al.   10617197

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYMIESKGGA IACMLLALLF LGTWPAIMTL TERRGRLPQH TYLDYTLTNL LAAVIIALTL 
61:	GEIGPSRPNF FTQLSQDNWQ SVMFAMAGGI VLSLGNLATQ YAWAYVGLSV TEVITASITV 
121:	VIGTTLNYFL DDRINRAEVL FPGVACFLIA VCFGSAVHKS NAADNKTKLQ NFKSLETTSS 
181:	FEMETISASN GLTKGKAKEG TAAFLIELEK QRAIKVFGKS TIIGLVITFF AGICFSLFSP 
241:	AFNLATNDQW HTLKHGVPKL NVYTAFFYFS ISAFVVALIL NIRFLYWPIL GLPRSSFKAY 
301:	LNDWNGRGWS FLAGFLCGFG NGLQFMGGQA AGYAAADAVQ ALPLVSTFWG ILLFGEYRRS 
361:	SRKTYTLLIS MLLMFIVAVA VLMASSGHRK