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2.A.7.19.3
Ureide Permease 5, UPS5 of 415 aas and 10 TMSs.  Proton-coupled transporter that transports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine, but not adenine. Mediates transport of uracil and 5-fluorouracil (a toxic uracil analog) (Schmidt et al. 2006).  Allantoin accumulation mediated by UPS5 confers salt stress tolerance (Lescano et al. 2016).

Accession Number:Q93Z75
Protein Name:Ureide permease 5
Length:413
Molecular Weight:44621.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ureide, Allantoin, Uric acid, Xanthine

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External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMIAQELGIY VVESKGGAIL CLLLSLLCLG TWPALMALLE RRGRLPQHTY LDYSITNFLA 
61:	AIFIAFVFGG IGESTHEAPS FITQLTQIQD NWPSVLFAMA GGVGLSIGNL ATQYSLAFVG 
121:	LSVTEVTAAS ITVVVGTTVN YFLDNGLNRA DILFSGVGCF MVAVCLGSAV HSSNSADIKA 
181:	KLGKLSGDCE TVTPEECQRL FGVEEEEEEE KEMENVKEGS AAFLIALENK RAIKVLGKSM 
241:	VVGLGITFFA GLSFSLFSPL FNLATNDQWH TLKQGVPKLI VYTAFFYFSL SCFVIAVALN 
301:	ISFLYKPVLD SPRSSFREYL SDWNGRGWAL AAGLLCGFGN GLQFMGGQAA GYAASDAVQA 
361:	LPLVSTFWGI YLFGEYRRSS TRTYALLVGM LVMFTVAVGL LMASAGERET RFT