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2.A.7.19.4
Ureide permease 2, UPS2, of 398 aas and 10 TMSs. Proton-coupled transporter that transports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine, but not adenine. Mediates high affinity transport of uracil and 5-fluorouracil (a toxic uracil analog). Mediates transport of free pyrimidines and may function during early seedling development in salvage pathways, by the utilization of pyrimidines from seed storage tissue (Schmidt et al. 2004). Km for uracil = 6 μM; for xanthine = 24 μM; for allantoin = 26 μM.

Accession Number:Q9ZQ89
Protein Name:Ureide permease 2
Length:398
Molecular Weight:43542.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Pyrimidines, 5-fluorouracil, Uric acid, Allantoin, Xanthine, Uracil

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FASTA formatted sequence
1:	MYLVESKGGA IACMLLALLS LGTWPAVLTL LERRGRLPQH TYLDYSITNL LAAIIIAFTF 
61:	GQIGSTKPDS PNFITQLAQD NWPSVMFAMA GGIVLSLGNL STQYAWALVG LSVTEVITSS 
121:	ITVVIGSTLN YFLDDKINKA EILFPGVACF LIAVCLGSAV HRSNADDNKA KLRDFETAKQ 
181:	EASGPSTEIG TNSSKDLETN VTTKPKEGTA RFLIELENTR AIKVFGKRKI IGLAITFFAG 
241:	LCFSLFSPAF NLATNDQWNR LKQGVPKLVV YTAFFYFSVS CFIIALILNV VFLYYPVLGL 
301:	PKSSFKAYLN DWNGRYWAFL AGFLCGFGNG LQFMGGQAAG YAAADSVQAL PLVSTFWGVV 
361:	LFGEYRRSSR KTYLLLFCML FMFISAVAVL MASSGHRK