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2.A.7.20.4
Chloroplastic chloroquine resistance transporter-1 of 447 aas and 10 TMSs, Clt-1.  Involved in thiol transport from the plastid to the cytosol. Transports both glutathione (GSH) and its precursor, gamma-glutamylcysteine (gamma-EC). Exhibits some functional redundancy with CLT3 in maintaining the root GSH pool (Maughan et al. 2010).

Accession Number:Q058P6
Protein Name:Protein CLT1, chloroplastic
Length:447
Molecular Weight:47925.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Plastid1 / Multi-pass membrane protein2
Substrate chloroquine

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MATTSSDRLI AGLTASIGSI ESRYANPAQS VSLICRNQIN GAPPIVLRSS RRSRLWLIEA 
61:	IPPAKSWNGS NDGDEDIKKS DTRNYAIGGT GGHAVAGKDD RTMEIVIAAA TTAALGVGNR 
121:	VLYKLALIPL KQYPFFLAQL STFGYVAVYF SILYFRYRAG IVTKEMLSVP KLPFLIVGVL 
181:	ESLALAAGMA AASNLSGPST TVLSQTFLVW QILFSIIFLG RRYRINQILG CTLVAFGVIV 
241:	SVASGSGAAH SFKDTGILWS LLMVFSFLLQ GADTVMKEVI FLDSKKRLKG ASLDLFVVNS 
301:	YGSIFQVICI ALLLPFLSKL WGIPFNQLPS YIRDGGACFL NIGSRITGCE GAPLLPVMFV 
361:	MMNMAYNISL LRLIKISSAV VSSLASTVSV PIAVYCFTLP LPYLGVASTL PRGFVAGTII 
421:	LVVGMLLYAW TPSTNTSDSI IPSPPST