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2.A.7.21.4
The orotate transporter, OroP (Defoor et al., 2007) (also, transports 5-fluoroorotate)

Accession Number:Q3SAW5
Protein Name:OroP
Length:307
Molecular Weight:33379.00
Species:Lactococcus lactis subsp. lactis bv. diacetylactis [44688]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Orotate

Cross database links:

RefSeq: YP_001098362.1   
Entrez Gene ID: 4929800   
Pfam: PF04657   

References (1)

[1] “The orotate transporter encoded by oroP from Lactococcus lactis is required for orotate utilization and has utility as a food-grade selectable marker.”  Defoor E.et.al.   17975072

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MYIYLAFALV GGFLLANQNP INADLRKIVG SPFLASGISN FVGSIFLGII TLVTSQTLFP 
61:	SFQFVGSHPV WIWIGGVLGG IFLTSNVLLF PRLGAVQTVI LPILGRILMG TLIDSFGWFH 
121:	AMQLPMTLMR FLGVIITLAG VIVAVVLPNL KEKEAETHQT NLLGWRIWAV IVGAMSAAQQ 
181:	AINGRLGVLL ENTAQATFVS FFIGFLAIFI VSLFIDRRLP KISELKKAKP WNGIGGFLGA 
241:	SIVFATVVAV PQIGAGLTIM MGLIGQILGS MLVQQFGWWR SSKYGIQIWQ IVGILIMLTG 
301:	IIFIKFL