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2.A.7.3.20
S-adenosylmethionine/S-adenosylhomocysteine transporter (SAM/SAH transporter) (SAMHT; CTL843).  May function in SAM uptake and SAH export, perhaps by an SAM/SAH antiport mechanism (Binet et al. 2011).

Accession Number:B0B8F4
Protein Name:S-adenosylmethionine/S-adenosylhomocysteine transporter
Length:327
Molecular Weight:36069.00
Species:Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) [471472]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate S-adenosylmethionine, S-adenosylhomocysteine

Cross database links:

eggNOG: COG0697 COG0697
HEGENOM: HOG000034803 HOG000034803
Entrez Gene ID: 5858034    5858034   
Pfam: PF00892    PF00892   
KEGG: ctb:CTL0843    ctb:CTL0843   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006810 P:transport
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006810 P:transport

References (4)

[1] “Chlamydia trachomatis: genome sequence analysis of lymphogranuloma venereum isolates.”  Thomson N.R.et.al.   18032721
[2] “Identification and characterization of the Chlamydia trachomatis L2 S-adenosylmethionine transporter.”  Binet R.et.al.   21558433
[3] “Chlamydia trachomatis: genome sequence analysis of lymphogranuloma venereum isolates.”  Thomson N.R.et.al.   18032721
[4] “Identification and characterization of the Chlamydia trachomatis L2 S-adenosylmethionine transporter.”  Binet R.et.al.   21558433

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVAVKALLFA CTLRTCVFKP CCDMAIFLIF LNAFIWSSSF ALSKSAMEAA APLFVTGSRM 
61:	VLAGVVLFGL LLCKRESLRL PRPAIMPIVL LSVIGFYLTN VLEFIGLQRL SSSTACFIYG 
121:	FSPFTAAFCS YVQLREVVTW KKLGGLSLGL VSYLVYLLFG GSEDVAEWGW QLGLPELLLI 
181:	AATCLSSYGW TLLRKLGRRC ESLSMTAINA YAMVIAGVLS LIHSAVTEVW NPVPVENPLL 
241:	FLQAIGALVI FSNLICYNLF AKLLRSFSST FLSFCNLVMP LFASFFGWLL LGESFPPGLL 
301:	FAVGFMVLGC RLIYHEEFRQ GYVLTSE