TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.7.9.11
The putative thiamine pyrophosphate transporter, SLC35E4

Accession Number:Q6ICL7
Protein Name:Solute carrier family 35 member E4
Length:350
Molecular Weight:36747.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Thiamine pyrophosphate

Cross database links:

Genevestigator: Q6ICL7 Q6ICL7 Q6ICL7
eggNOG: prNOG14104 NOG129799 NOG129799
HEGENOM: HBG282230 HOG000137347 HOG000137347
Entrez Gene ID: 339665   
Pfam: PF00892    PF03151   
KEGG: hsa:339665    hsa:339665    hsa:339665   

Gene Ontology

GO:0016021 C:integral to membrane

References (6)

[1] “A genome annotation-driven approach to cloning the human ORFeome.”  Collins J.E.et.al.   15461802
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “A genome annotation-driven approach to cloning the human ORFeome.”  Collins J.E.et.al.   15461802
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[5] “A genome annotation-driven approach to cloning the human ORFeome.”  Collins J.E.et.al.   15461802
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MCRCPPEHHD GRMTSAEVGA AAGGAQAAGP PEWPPGSPQA LRQPGRARVA MAALVWLLAG 
61:	ASMSSLNKWI FTVHGFGRPL LLSALHMLVA ALACHRGARR PMPGGTRCRV LLLSLTFGTS 
121:	MACGNVGLRA VPLDLAQLVT TTTPLFTLAL SALLLGRRHH PLQLAAMGPL CLGAACSLAG 
181:	EFRTPPTGCG FLLAATCLRG LKSVQQSALL QEERLDAVTL LYATSLPSFC LLAGAALVLE 
241:	AGVAPPPTAG DSRLWACILL SCLLSVLYNL ASFSLLALTS ALTVHVLGNL TVVGNLILSR 
301:	LLFGSRLSAL SYVGIALTLS GMFLYHNCEF VASWAARRGL WRRDQPSKGL