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2.A.7.9.24
The phosphoenolpyruvate/phosphate translocator, pPT, of 524 aas in the outer membranes of apicoplasts, vestigial plastids in apicomplexan parasites such as Plasmodium. Transports glucose-6 P and triose-3 Ps via an inorganic phosphate antiport mechanism.  Apicomplexan parasites are dependant on their apicoplasts for synthesis of various molecules that they are unable to scavenge in sufficient quantity from their host. They import carbon, energy and reducing power to drive anabolic synthesis in the organelle. pPT is targeted into the outer apicoplast membrane via a transmembrane domain that acts as a recessed signal anchor to direct the protein into the endomembrane system. A tyrosine in the cytosolic N-terminus of the protein is essential for targeting (Lim et al. 2016).

Accession Number:Q8I0U9
Protein Name:Phosphoenolpyruvate/phosphate translocator
Length:524
Molecular Weight:59789.00
Species:Plasmodium falciparum (isolate 3D7) [36329]
Number of TMSs:9
Substrate Phosphoenolpyruvate, phosphate

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FASTA formatted sequence
1:	MNVLTRTLII TIFFNLQIYI GKCLNHDNIK NIKNVPMNFH LKNTNGKIYQ KNKRPSQINR 
61:	KNTNKQAFNI PVFSIPNYKP KYNTCTKTKN IAFVNSRINQ AHNRNIQVTK AAELNAIKKI 
121:	KNDKKFTLFN SGNRDNIKTY EHDINKGIID DISTTNNSYS NIGDTSENTY QPNNFNNTLT 
181:	EKKPCTFLNK AVEVGKTVSL LGMWYVCNIF YNIENKKALN ILNMPITIAI TQIYVGLPIF 
241:	LIPWLLKLRN QPELFYDEQE LKRINMSDRN ALIKGFQKYV LFLKKYSSIM KQSIYHGYAH 
301:	LLSVIAMGAG AISFVHIVKA SAPLFAAFFS YFFMNNKMSI YTYSSLVPIV FGVSLASIKE 
361:	LSFTYKALYS TLSANVLSTM RAIEAKIMMG KNLDKLGRNL TPENIFALLT LSSAIFLTPA 
421:	LYIDSHKWKD AYEYLMNNKN VLKVLGRHVL MSGVWFYLYN QLSFISLNRL NHITHAVAST 
481:	VKRVFLILTS YFIFGTKFSF LGGLGSSIAV GGTFVYSLVK KKFG