TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.7.9.4
Sly41p (transport function unknown)

Accession Number:P22215
Protein Name:SLY4 aka Sly41p aka SLY41 aka YOR307C aka O5663
Length:453
Molecular Weight:50903.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P22215
eggNOG: fuNOG06549
HEGENOM: HBG398630
DIP: DIP-2919N
RefSeq: NP_014952.1   
Entrez Gene ID: 854484   
Pfam: PF03151   
KEGG: sce:YOR307C   

Gene Ontology

GO:0005783 C:endoplasmic reticulum
GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0006888 P:ER to Golgi vesicle-mediated transport

References (8)

[1] “Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.”  Dascher C.et.al.   1990290
[2] “Sequencing of a 35.71 kb DNA segment on the right arm of yeast chromosome XV reveals regions of similarity to chromosomes I and XIII.”  Pearson B.M.et.al.   8896266
[3] “Sequence and analysis of a 36.2 kb fragment from the right arm of yeast chromosome XV reveals 19 open reading frames including SNF2 (5' end), CPA1, SLY41, a putative transport ATPase, a putative ribosomal protein and an SNF2 homologue.”  Poirey R.et.al.   9153758
[4] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[5] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[6] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[7] “Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.”  Smolka M.B.et.al.   17563356
[8] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MIQTQSTAIK RRNSVHKNLF DPSLYQIPEP PRGGFQHQKK EYSKETFSNQ VFGYDITSLK 
61:	KRFTQLFPSN IQGYLPEVDL RITIICSIWY VTSSISSNLS KAILRTFNHP IALTELQFLV 
121:	SAVLCVGFAS IVNLFRLPRL KHTKFSKALN SFPDGILPEY LDGNFRSSIL HKFLVPSKLV 
181:	LMTTFPMGIF QFIGHITSHK AVSMIPVSLV HSVKALSPII TVGYYKFFEH RYYNSMTYYT 
241:	LLLLIFGVMT TCWSTHGSKR ASDNKSGSSL IGLLFAFISM IIFVAQNIFA KNILTIRRKV 
301:	GILPSSSTDD VTSKEGQPSL DKTRFSPLQV DKITILFYCS CIGFSLTLLP FLTGELMHGG 
361:	SVINDLTLET VALVAIHGIA HFFQAMLAFQ LIGLLSSINY SVANIMKRIV VISVALFWET 
421:	KLNFFQVFGV ILTIAGLYGY DKWGLSKKDG RQA