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2.A.71.1.3
FT1 folate/biopterin transporter.  This protein is nearly identical to the functionally characterized protein from L. infantum (2.A.71.1.5) which is a high affinity S-adenosyl methione uptake porter.  Therefore the annotation shown above may be incorrect and this protein may also be an S-adenosyl methionine uptake porter (Dridi et al. 2010). 

Accession Number:Q9UAC2
Protein Name:FT1
Length:704
Molecular Weight:76523.00
Species:Leishmania donovani [5661]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cytoplasm1 / Peripheral membrane protein2
Substrate Biopterin, folate, S-adenosylmethionine

Cross database links:

Pfam: PF03092   

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSYKEAAPKR EKDAAGAAAV PEAAAAGNDG KYIHPEAASL FARCPWARRV PVFGEAVKGY 
61:	GLKFIVALGA SNLLCKGVAD QILYGQTYAM MIDRYGIDVA RYQRLSSIST MGWSIKAFTA 
121:	MLCDGFAFLG YTKRWYMFIS CVGGGAFALI YGLLPAKEAS ANVACAFIFL SSWGKANVDI 
181:	LSQGHYSRLM RQNPKPGPAL VSWMWFCIMI GSLIATVMNG PLADAGKPQI SIFVSAALQA 
241:	ITCVFYLFNW YGEKKNRVLR SEDALFILEE TRKERERLGL EGVNNGTAGA QHGGAAKGKR 
301:	SPQRSHSDEG VEGAVRDALN DGQRDNGELV QDVYDDAYDD GEEVAEGEVY YGKPPVPCLF 
361:	GLFEMNREVI SKNWKIFVYS VVMTCAVIAM LCANILADTL GLLVACVVVS TICCAASFWA 
421:	LPLVIAKANV FAYLDKAVSI RVSGPLNAFY LNTYGCPGNL PNFTYTFYNT VAGVINTIVG 
481:	MITVTLFNFL FAKHGYRLTF IVTTIMQVLA ALFDIIMVKR WNLYIGIPDH AMYIWGDAVV 
541:	GEIVYMLGFM PQIVLLSRLC PRGSESVVYA LMAGFARLGR TTAASLGAIL LEYGLPVFKT 
601:	QDDGSRCNYD NLPLLLFLCS MCTPLLAIPL SIILLPKARI CDDIDIDGKV VRQAVDKQVA 
661:	AAPLSSSDSD AVMNAEPLHG NKADEREAAR GEAVEGKRAG ASEK