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2.A.71.1.4
FT1 (ESAG10) folate/biopterin transporter

Accession Number:Q07492
Protein Name:ESAG10
Length:686
Molecular Weight:75897.00
Species:Trypanosoma brucei brucei [5691]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate folate, Biopterin

Cross database links:

eggNOG: euNOG10377
Pfam: PF03092   

References (1)

[1] “A new VSG expression site-associated gene (ESAG) in the promoter region of Trypanosoma brucei encodes a protein with 10 potential transmembrane domains.”  Gottesdiener K.M.et.al.   8183314

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRFLSFKHSF VLVLCFFSAR CNNKVALSFC AEYKVEPKVT VVKTFILVGI YLVTMTTSPN 
61:	ACQDQPPQHS APQAHEAECT THKLSAEKTM DARPVHPDAR ALFQQLPCVW RIPVFGTAVE 
121:	AFGPRCVLAL GLSELFGKGI AHDMIRTTLF PMFTYTFGAD AKLYQRMGGM SSLGYAMKPF 
181:	AAMFSDLFAL FGYTKRWYLA LSCVVGSTVA IVYGSLPGEL SYVPVAGILV FVMAFTKGIL 
241:	DILTQGHYSR LIRRVPLAGP SLVSWVWWCV LTGSLIASSI VGPLTDKKLQ RVAVFISAGI 
301:	QFVPTIFFIM NWYGERRNRE ERAYDLTVLR KEQLEREADA AGLQGSEETS GSLDNPSDAE 
361:	EVAEAGTRIL TCCCGAFEVN REVFARNKKV VFYCMLLTLG AMGMVLVTVL GTRLQLLITS 
421:	VLASFTLCGL GFVALPLVIA KANMFTFISR VAYIQLPGAI DNVFMATPDC FPGGPNFSYF 
481:	YYSTVGNMIG AVGGVIGVTL FRYVFSKRSY RLTFIVTTLI EIVSSIFDII IVERWNRPYV 
541:	SDHVVFVLGD QIIHQVCYMM HFMPTVILIS RLCPSGYESA VYSVLAGCAH FGRSVSNTLG 
601:	WLLMEYVWNV QSDIKVGPCD FSNVKWLLLV GHFATPLISI PLVFLLIPAA RLCDVLDENG 
661:	KAITKEAEDV RAPSNDSPRM REPTAN