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2.A.72.1.2
Probable potassium transport system protein Kup

Accession Number:Q8TL61
Protein Name:Probable potassium transport system protein kup
Length:603
Molecular Weight:67136.00
Species:Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [188937]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

eggNOG: COG3158
Entrez Gene ID: 1475073   
Pfam: PF02705   
KEGG: mac:MA3179   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015079 F:potassium ion transmembrane transporter activity

References (1)

[1] “The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity.”  Galagan J.E.et.al.   11932238

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFSKSDFRGI INSMGLVFGD IGTSPIYTLT VIFLLTRPTE VHVIGVLSLI IWTLITLVTV 
61:	EYAWLAMSLG KKGEGGTIVL KELLVPLIKS GRNAAFITLL AYIGVSFLVG DGVITPAISI 
121:	LSAVEGLRII PDFQDIGQGA IMFIAGIIAV ALFSVQSKGT EEITWVFGPV MVLWFASLAF 
181:	SGIASIFYTP GVLRAINPYY AISFLLHNGF TGFFVLSEVI LCATGGEALY ADMGHLGREP 
241:	ILKAWRLVFS ALVLNYLGQG AFIIRNPESK NILFEMINQQ AEVIYIPFLI LSITATIIAS 
301:	QAMISGMFSI VYQGITTRII PMLKIDYTSG KLRSQIYIGA VNWLLLISVL FMIFEFRDSH 
361:	RLAAAYGLAV TGTMSITGLM MTLIFYLKGR MFRSFVSLFV TVIDVVFLLS NTYKIPHGGY 
421:	WSIVIAAIAF SLIIIYTSGQ KKLYELMNPM KIGDFLEKYK QVYASENKIS GTALFFARDI 
481:	NYVPRYISNV MFENNIIYED NIFISIIKCE SPFGVKSSFA KDLAKGLRVF EINVGYMEVI 
541:	DVVQILKDKG IQEKTIFYGI EDILTSNLIW KVFSVIKKLS PSFVQFYKLP SDKLHGVLTR 
601:	FEM