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2.A.76.1.4
O-aetylserine/cysteine/azaserine exporter, EamB or YfiK (Franke et al., 2003).  

Accession Number:P38101
Protein Name:YfiK aka B2578
Length:195
Molecular Weight:21248.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate O-acetylserine, Cysteine, Azaserine

Cross database links:

Genevestigator: P38101
EchoBASE: EB2339
EcoGene: EG12445
eggNOG: COG1280
HEGENOM: HBG759042
RefSeq: AP_003164.1    NP_417073.1   
Entrez Gene ID: 947065   
Pfam: PF01810   
BioCyc: EcoCyc:EG12445-MONOMER    ECOL168927:B2578-MONOMER   
KEGG: ecj:JW2562    eco:b2578   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006865 P:amino acid transport

References (5)

[1] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “YfiK from Escherichia coli promotes export of O-acetylserine and cysteine.”  Franke I.et.al.   12562784
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTPTLLSAFW TYTLITAMTP GPNNILALSS ATSHGFRQST RVLAGMSLGF LIVMLLCAGI 
61:	SFSLAVIDPA AVHLLSWAGA AYIVWLAWKI ATSPTKEDGL QAKPISFWAS FALQFVNVKI 
121:	ILYGVTALST FVLPQTQALS WVVGVSVLLA MIGTFGNVCW ALAGHLFQRL FRQYGRQLNI 
181:	VLALLLVYCA VRIFY