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2.A.8.1.12
The putative histidine porter, YuiF. Regulated by Histidine repressor HisR (Ravcheev et al. 2011)

Accession Number:O32105
Protein Name:Putative amino acid transporter yuiF
Length:442
Molecular Weight:45937.00
Species:bacillus subtilis [1423]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Histidine

Cross database links:

HEGENOM: HBG289792
RefSeq: NP_391084.1   
Entrez Gene ID: 937212   
Pfam: PF03553   
BioCyc: SUBTI:BSU32040-MONOMER   
KEGG: bsu:BSU32040   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015385 F:sodium:hydrogen antiporter activity
GO:0006885 P:regulation of pH
GO:0006814 P:sodium ion transport

References (1)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNAVVIAVLL MLVLSLLRVN IVIALIIGAL AGGLTGGLGL GETVKAFTDG LGGNATVAVS 
61:	YAMLGAFAAA LTKTGLPDAM VEASVKLIGN KEDSRKKALS KVLIVLIILI VSCFSQNVVP 
121:	VHIAFIPVLI PPLLKIFNEL EMDRRLIACV ITFGLTAPYI LLPVGFGQIF QGMLKDNMAD 
181:	AGLNVPLADI PYALIIPVAG MVVGLILSVI VYRKPKQYET KDISGAEASP YTRKSIGIAV 
241:	LAIVVSLGVQ LYLSQTLGVE GMIMGALAGL IVLFVSGVMK RDEADSLITD GMVLMAFIGF 
301:	VMLVAAGFSN VLTKTGDVES LVKTSAGFIG HSQSLGALLM LIVGLLITMG IGSSFATIPV 
361:	ITTIFVPLCM QLGFSPMATI AIIGAAAALG DAGSPASDST LGPTSGLSAD GQHHHIWDTC 
421:	VPTFIFYNIP LVIFGWIAAL VL