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2.A.81.1.3
Succinate exporter, SucE1. Induced under microaerobic and anaerobic conditions when succinate is produced from glucose via the reductive tricarboxylic acid cycle. Exhibits succinate counterflow (self exchange) (Fukui et al., 2011).

Accession Number:Q8NNI8
Protein Name:Uncharacterized transporter Cgl2211/cg2425
Length:539
Molecular Weight:57150.00
Species:Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [196627]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Succinate

Cross database links:

eggNOG: COG2985
HEGENOM: HOG000013110
Entrez Gene ID: 1020162    3344478   
Pfam: PF06826    PF02080   
KEGG: cgb:cg2425    cgl:NCgl2130   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008324 F:cation transmembrane transporter activity
GO:0006813 P:potassium ion transport

References (1)

[1] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSFLVENQLL ALVVIMTVGL LLGRIKIFGF RLGVAAVLFV GLALSTIEPD ISVPSLIYVV 
61:	GLSLFVYTIG LEAGPGFFTS MKTTGLRNNA LTLGAIIATT ALAWALITVL NIDAASGAGM 
121:	LTGALTNTPA MAAVVDALPS LIDDTGQLHL IAELPVVAYS LAYPLGVLIV ILSIAIFSSV 
181:	FKVDHNKEAE EAGVAVQELK GRRIRVTVAD LPALENIPEL LNLHVIVSRV ERDGEQFIPL 
241:	YGEHARIGDV LTVVGADEEL NRAEKAIGEL IDGDPYSNVE LDYRRIFVSN TAVVGTPLSK 
301:	LQPLFKDMLI TRIRRGDTDL VASSDMTLQL GDRVRVVAPA EKLREATQLL GDSYKKLSDF 
361:	NLLPLAAGLM IGVLVGMVEF PLPGGSSLKL GNAGGPLVVA LLLGMINRTG KFVWQIPYGA 
421:	NLALRQLGIT LFLAAIGTSA GAGFRSAISD PQSLTIIGFG ALLTLFISIT VLFVGHKLMK 
481:	IPFGETAGIL AGTQTHPAVL SYVSDASRNE LPAMGYTSVY PLAMIAKILA AQTLLFLLI