TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*2.A.81.1.1









The L-aspartate:L-alanine exchanger, AspT.  A mutant, R76K, has higher activity than the AspT-WT (R76), whereas R76D and R76E have lower activity than AspT-WT. Thus, R76 is involved in AspT substrate transport (Suzuki et al. 2016).

Bacteria
Firmicutes
AspT of Tetragenococcus halophila sp. D10 (Q8L3K8)
*2.A.81.1.2









The putative cobalt porter, CbtD (Rodionov et al. 2003)

Bacteria
Bacteroidetes/Chlorobi group
CbtD of Bacteroides fragilis (Q5LCC7)
*2.A.81.1.3









Succinate exporter, SucE1. Induced under microaerobic and anaerobic conditions when succinate is produced from glucose via the reductive tricarboxylic acid cycle. Exhibits succinate counterflow (self exchange) (Fukui et al., 2011).

Bacteria
Actinobacteria
SucE1 of Corynebacterium glutamicum (Q8NNI8)
*2.A.81.1.4









Putative transporter, YbjL

Bacteria
Proteobacteria
YbjL of E. coli
*2.A.81.1.5









Putative transport protein YidE
Bacteria
Proteobacteria
YidE of Escherichia coli
*2.A.81.1.6









Aspartate:alanine antiporter, AspT, of 561 aas. AspT has 7 TMSs, a large cytoplasmic loop containing approximately 200 aas between TMS4 and TMS5, a cytoplasmic N-terminus, and a periplasmic C-terminus (Fujiki et al. 2007).

Bacteria
Proteobacteria
AspT of Pseudomonas dacunhae (Comamonas testosteroni)
*2.A.81.2.1









Homologue of AspT (384 aas; 10 putative TMSs; with potential membrane embedded loops between TMSs 4 and 5 and TMSs 9 and 10 (the two halves are internally duplicated)). The central hydrophilic domain in 2.A.81.1.1 is absent in this homologue.

Archaea
Euryarchaeota
AspT homologue of Halobacterium sp. NRC-1 (AAC82885)
*2.A.81.2.2









YidE/YbjL duplication protein

Bacteria
Thermotogae
YidE homologue of Thermosipho melanesiensis