TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*2.A.82.1.1









The organic solute transporter, OSTα/OSTβ (transports taurocholate, estrone sulfate, digoxin, and prostaglandin E2)
Eukaryota
Metazoa
OSTα/OSTβ of the little skate, Raja erinacea
OSTα (AAK14805)
OSTβ (AAK14806)
*2.A.82.1.2









The organic solute transporter OSTα/OSTβ or SLC51A/SLC51B (transports the same anions as the 2.A.82.1.1 system) (The ileal enterocyte basolateral bile acid transporter; uses facilitated diffusion vian an anion:anion antiport mechanism with sulfate or bicarbonate as the counter anion) (Dawson et al., 2005).  Transports steroid-derived molecules as well as glycine and taurine conjugated bile acids (Ballatori et al. 2013).  Heterodimerization increases stability, facilitates post-translational modification and is required for delivery to the plasma membrane.  This system is essential for intestinal bile acid and dietary lipid absorption (Ballatori et al. 2013).

Eukaryota
Metazoa
OSTα/OSTβ of Homo sapiens
OSTα (AAP23993)
OSTβ (AAP23992)
*2.A.82.1.3









Transmembrane protein 184B (Putative MAPK-activating protein FM08)
Eukaryota
Metazoa
TMEM184B of Homo sapiens
*2.A.82.1.4









Organic solute transporter alpha-like protein C18A3.4
Eukaryota
Metazoa
C18A3.4 of Caenorhabditis elegans
*2.A.82.1.5









Ostα subunit homologue

Eukaryota
Bacillariophyta
Ostα of Thalassiosira oceanica
*2.A.82.1.6









Uncharacterized protein of 335 aas and 7 TMSs.

Eukaryota
Metazoa
UP of Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
*2.A.82.1.7









Uncharacteerized protein of 356 aas and 8 TMSs.

Eukaryota
Entamoebidae
UP of Entamoeba histolytica