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2.A.82.1.3
Transmembrane protein 184B (Putative MAPK-activating protein FM08)

Accession Number:Q9Y519
Protein Name:Transmembrane protein 184B
Length:407
Molecular Weight:45562.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: Q9Y519 Q9Y519
eggNOG: NOG240726 NOG240726
Entrez Gene ID: 25829    25829   
Pfam: PF03619    PF03619   
KEGG: hsa:25829    hsa:25829   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0016021 C:integral to membrane

References (24)

[1] “Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.”  Matsuda A.et.al.   12761501
[2] “A genome annotation-driven approach to cloning the human ORFeome.”  Collins J.E.et.al.   15461802
[3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[4] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[5] “The DNA sequence of human chromosome 22.”  Dunham I.et.al.   10591208
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[7] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[8] “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.”  Olsen J.V.et.al.   17081983
[9] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[10] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[11] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.”  Gauci S.et.al.   19413330
[12] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332
[13] “Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.”  Matsuda A.et.al.   12761501
[14] “A genome annotation-driven approach to cloning the human ORFeome.”  Collins J.E.et.al.   15461802
[15] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[16] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[17] “The DNA sequence of human chromosome 22.”  Dunham I.et.al.   10591208
[18] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[19] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[20] “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.”  Olsen J.V.et.al.   17081983
[21] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[22] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[23] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.”  Gauci S.et.al.   19413330
[24] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTVRGDVLAP DPASPTTAAA SPSVSVIPEG SPTAMEQPVF LMTTAAQAIS GFFVWTALLI 
61:	TCHQIYMHLR CYSCPNEQRY IVRILFIVPI YAFDSWLSLL FFTNDQYYVY FGTVRDCYEA 
121:	LVIYNFLSLC YEYLGGESSI MSEIRGKPIE SSCMYGTCCL WGKTYSIGFL RFCKQATLQF 
181:	CVVKPLMAVS TVVLQAFGKY RDGDFDVTSG YLYVTIIYNI SVSLALYALF LFYFATRELL 
241:	SPYSPVLKFF MVKSVIFLSF WQGMLLAILE KCGAIPKIHS ARVSVGEGTV AAGYQDFIIC 
301:	VEMFFAALAL RHAFTYKVYA DKRLDAQGRC APMKSISSSL KETMNPHDIV QDAIHNFSPA 
361:	YQQYTQQSTL EPGPTWRGGA HGLSRSHSLS GARDNEKTLL LSSDDEF