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2.A.86.1.4
Autoinducer-2 (AI-2) exporter, TqsA (YdgG).  Plays a role in biofilm formation (Nobre et al. 2009).

Accession Number:P0AFS5
Protein Name:YdgG
Length:344
Molecular Weight:37543.00
Species:Escherichia coli [83333]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Autoinducer-2

Cross database links:

Genevestigator: P0AFS5
EchoBASE: EB3687
EcoGene: EG13928
eggNOG: COG0628
HEGENOM: HBG439472
RefSeq: AP_002222.1    NP_416118.1   
Entrez Gene ID: 946142   
Pfam: PF01594   
BioCyc: EcoCyc:G6859-MONOMER    ECOL168927:B1601-MONOMER   
KEGG: ecj:JW1593    eco:b1601   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0009372 P:quorum sensing
GO:0006810 P:transport

References (5)

[1] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.”  Aiba H.et.al.   9097039
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[5] “YdgG (TqsA) controls biofilm formation in Escherichia coli K-12 through autoinducer 2 transport.”  Herzberg M.et.al.   16385049

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MAKPIITLNG LKIVIMLGML VIILCGIRFA AEIIVPFILA LFIAVILNPL VQHMVRWRVP 
61:	RVLAVSILMT IIVMAMVLLL AYLGSALNEL TRTLPQYRNS IMTPLQALEP LLQRVGIDVS 
121:	VDQLAHYIDP NAAMTLLTNL LTQLSNAMSS IFLLLLTVLF MLLEVPQLPG KFQQMMARPV 
181:	EGMAAIQRAI DSVSHYLVLK TAISIITGLV AWAMLAALDV RFAFVWGLLA FALNYIPNIG 
241:	SVLAAIPPIA QVLVFNGFYE ALLVLAGYLL INLVFGNILE PRIMGRGLGL STLVVFLSLI 
301:	FWGWLLGPVG MLLSVPLTII VKIALEQTAG GQSIAVLLSD LNKE