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2.A.86.1.7
Rv0205 (UFP0118) protein (376 aas, 8 putative TMSs) (may function with a heme uptake transporter) (TC# 2.A.6.5.5)

Accession Number:O53656
Protein Name:UPF0118 membrane protein Rv0205/MT0215
Length:367
Molecular Weight:38038.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Heme

Cross database links:

HEGENOM: HBG699212 HBG699212
Entrez Gene ID: 886766    923108   
Pfam: PF01594   
KEGG: mtc:MT0215    mtu:Rv0205    mtc:MT0215    mtu:Rv0205   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0040007 P:growth

References (4)

[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.”  Fleischmann R.D.et.al.   12218036
[3] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[4] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.”  Fleischmann R.D.et.al.   12218036

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSASLDDASV APLVRKTAAW AWRFLVILAA MVALLWVLNK FEVIVVPVLL ALMLSALLVP 
61:	PVDWLDSRGL PHAVAVTLVL LSGFAVLGGI LTFVVSQFIA GLPHLVTEVE RSIDSARRWL 
121:	IEGPAHLRGE QIDNAGNAAI EALRNNQAKL TSGALSTAAT ITELVTAAVL VLFTLIFFLY 
181:	GGRSIWQYVT KAFPASVRDR VRAAGRAGYA SLIGYARATF LVALTDAAGV GAGLAVMGVP 
241:	LALPLASLVF FGAFIPLIGA VVAGFLAVVV ALLAKGIGYA LITVGLLIAV NQLEAHLLQP 
301:	LVMGRAVSIH PLAVVLAIAA GGVLAGVVGA LLAVPTVAFF NNAVQVLLGG NPFADVADVS 
361:	SDHLTEV