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2.A.87.1.2
Riboflavin transporter RibU (Riboflavin ECF transporter S component RibU or YpaA). Regulated by FMN riboswitch (Rodionov et al. 2009). RibU-mediated riboflavin uptake was sensitive to protonophores and reduced in the absence of glucose, demonstrating that the protein requires metabolic energy for substrate translocation (Vogl et al. 2007).

Accession Number:P50726
Protein Name:YpaA
Length:190
Molecular Weight:20553.00
Species:Bacillus subtilis [1423]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate riboflavin

Cross database links:

HEGENOM: HBG617336
RefSeq: NP_390186.1   
Entrez Gene ID: 938970   
KEGG: bsu:BSU23050   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (2)

[1] “Sequence analysis of the Bacillus subtilis chromosome region between the serA and kdg loci cloned in a yeast artificial chromosome.”  Sorokin A.V.et.al.   8760912
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKVKKLVVVS MLSSIAFVLM LLNFPFPGLP DYLKIDFSDV PAIIAILIYG PLAGIAVEAI 
61:	KNVLQYIIQG SMAGVPVGQV ANFIAGTLFI LPTAFLFKKL NSAKGLAVSL LLGTAAMTIL 
121:	MSILNYVLIL PAYTWFLHSP ALSDSALKTA VVAGILPFNM IKGIVITVVF SLIFIKLKPW 
181:	IEQQRSAHIH