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2.A.88.1.9
Biotin transporter, BioY (Biotin ECF transporter S component) (Hebbeln et al., 2007; Rodionov et al., 2009).

Accession Number:O07620
Protein Name:Probable biotin transporter bioY
Length:186
Molecular Weight:20010.00
Species:bacillus subtilis [1423]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Biotin

Cross database links:

HEGENOM: HBG672824
RefSeq: NP_388918.1   
Entrez Gene ID: 939321   
Pfam: PF02632   
BioCyc: SUBTI:BSU10370-MONOMER   
KEGG: bsu:BSU10370   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0009102 P:biotin biosynthetic process
GO:0006810 P:transport

References (4)

[1] “The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene.”  Noback M.A.et.al.   9579061
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “RNA expression analysis using an antisense Bacillus subtilis genome array.”  Lee J.M.et.al.   11717296
[4] “Conservation of the biotin regulon and the BirA regulatory signal in Eubacteria and Archaea.”  Rodionov D.A.et.al.   12368242

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLKLIDMMHI AIFTALMAVL GFMPPLFLSF TPVPITLQTL GVMLAGSILR PKSAFLSQLV 
61:	FLLLVAFGAP LLPGGRGGFG VFFGPSAGFL IAYPLASWLI SLAANRLRKV TVLRLFFTHI 
121:	VFGIIFIYLL GIPVQAFIMH IDLSQAAFMS LAYVPGDLIK AAVSAFLAIK ITQALSLSDT 
181:	MFTKGG