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2.A.88.3.1
Thiamin transporter, ThiT (Thiamin ECF transporter S component) (Rodionov et al. 2002; Rodionov et al. 2009).

Accession Number:O32074
Protein Name:Proton-coupled thiamine transporter thiT
Length:192
Molecular Weight:20452.00
Species:Bacillus subtilis [1423]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate thiamin

Cross database links:

HEGENOM: HBG421996
RefSeq: NP_390977.1   
Entrez Gene ID: 937137   
Pfam: PF09515   
BioCyc: SUBTI:BSU30990-MONOMER   
KEGG: bsu:BSU30990   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006810 P:transport

References (3)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[2] “Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms.”  Rodionov D.A.et.al.   12376536
[3] “Isolation and characterization of new thiamine-deregulated mutants of Bacillus subtilis.”  Schyns G.et.al.   16291685

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNQSKQLVRL IEIAIMTAAA VILDIVSGMF LSMPQGGSVS IMMIPIFLIS FRWGVKAGLT 
61:	TGLLTGLVQI AIGNLFAQHP VQLLLDYIVA FAAIGISGCF ASSVRKAAVS KTKGKLIVSV 
121:	VSAVFIGSLL RYAAHVISGA VFFGSFAPKG TPVWIYSLTY NATYMVPSFI ICAIVLCLLF 
181:	MTAPRLLKSD KA