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2.A.88.3.3
Thiamin transporter, ThiT (Thiamin ECF transporter S component) (Rodionov et al. 2002; Rodionov et al. 2009).    

Accession Number:Q037U3
Protein Name:Thiamine transporter ThiT
Length:201
Molecular Weight:21249.00
Species:Lactobacillus casei (strain ATCC 334) [321967]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate thiamin

Cross database links:

eggNOG: COG3859
HEGENOM: HOG000013022
Entrez Gene ID: 4420237   
Pfam: PF09515   
KEGG: lca:LSEI_1757   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006810 P:transport

References (3)

[1] “Comparative genomics of the lactic acid bacteria.”  Makarova K.S.et.al.   17030793
[2] “Identification of genes encoding the folate- and thiamine-binding membrane proteins in Firmicutes.”  Eudes A.et.al.   18776013
[3] “A novel class of modular transporters for vitamins in prokaryotes.”  Rodionov D.A.et.al.   18931129

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQQHKQLVVI LETAIIAAFA MALTYIPHTT GVSAIELNYG LIPIAVLAMR RGLVPAAWAG 
61:	FVWGILDLIL RGIGGGSVLN PLQGILEYPI AFTLVGLMGL TFASFQKAVR GSEKVKASGY 
121:	AFAGIIIGTF AKYFIHFIAG VVFWGAYAPK GTNVWVYSLI VNGGSALFST VLTIVVVGVL 
181:	LTVAPQLFVA KDGKSFSTKA A