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2.A.89.3.5
Nodulin-like2.1 (At3g25190) Iron regulated; involved in Fe homeostasis (Gollhofer et al., 2011).

Accession Number:Q9LSF6
Protein Name:Vacuolar iron transporter homolog 2.1
Length:219
Molecular Weight:23211.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Fe2+

Cross database links:

Genevestigator: Q9LSF6
eggNOG: COG1814
HEGENOM: HOG000096548
Entrez Gene ID: 822112   
Pfam: PF01988   
KEGG: ath:AT3G25190   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005774 C:vacuolar membrane
GO:0071369 P:cellular response to ethylene stimulus
GO:0071281 P:cellular response to iron ion
GO:0071732 P:cellular response to nitric oxide
GO:0006811 P:ion transport
GO:0055072 P:iron ion homeostasis

References (4)

[1] “Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones.”  Sato S.et.al.   10819329
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “An Arabidopsis basic helix-loop-helix leucine zipper protein modulates metal homeostasis and auxin conjugate responsiveness.”  Rampey R.A.et.al.   17028341
[4] “Members of a small family of nodulin-like genes are regulated under iron deficiency in roots of Arabidopsis thaliana.”  Gollhofer J.et.al.   21411332

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTSNVQLSET NSPRNQKTRP RAEKEEVDYM QRAQWLRAAL LGANDGLVTV ASLMMGVGSI 
61:	KEDVKAMLLV GFAGLVAGAC SMAIGEFVSV CTQRDIETAQ MKRAIEHKTS LSAIDEQEEE 
121:	EKKERLPNPG QAAIASALAF SVGAAMPLLG AVFIENHKVR MVVVAVVATI ALVVFGVTGA 
181:	VLGKTSVVKS SVRVVIGGWM AMALTFGLTK FIGSAAMQI