TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.9.2.1
Chloroplast protein, ALBINO3 (Alb3). Inserts a subset of light harvesting chlorophyll-binding proteins) (Gerdes et al., 2006). SRP43 (3.A.5.1.2) and the translocase, Alb3, interact directly (Dünschede et al., 2011). SRP43 is an ATP-independent chaperone containing ankyrin repeats required for the biogenesis of the most abundant class of membrane proteins, the light-harvesting chlorophyll a/b-binding proteins (LHCPs) (McAvoy et al. 2018).

Accession Number:Q8LBP4
Protein Name:Inner membrane protein ALBINO3, chloroplastic
Length:462
Molecular Weight:50245.00
Species: [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Plastid1 / Multi-pass membrane protein2
Substrate proteins

Cross database links:

Genevestigator: Q8LBP4
HEGENOM: HBG560622
RefSeq: NP_180446.1    NP_850125.1   
Entrez Gene ID: 817429   
Pfam: PF02096   

Gene Ontology

GO:0009535 C:chloroplast thylakoid membrane
GO:0016021 C:integral to membrane
GO:0005515 F:protein binding
GO:0045038 P:protein import into chloroplast thylakoid m...
GO:0051205 P:protein insertion into membrane
GO:0010027 P:thylakoid membrane organization

References (7)

[1] “ALBINO3, an Arabidopsis nuclear gene essential for chloroplast differentiation, encodes a chloroplast protein that shows homology to proteins present in bacterial membranes and yeast mitochondria.”  Sundberg E.et.al.   9165749
[2] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.”  Lin X.et.al.   10617197
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Chloroplast Oxa1p homolog albino3 is required for post-translational integration of the light harvesting chlorophyll-binding protein into thylakoid membranes.”  Moore M.et.al.   10636840
[5] “Distinct Albino3-dependent and -independent pathways for thylakoid membrane protein insertion.”  Woolhead C.A.et.al.   11524428
[6] “Chloroplast YidC homolog Albino3 can functionally complement the bacterial YidC depletion strain and promote membrane insertion of both bacterial and chloroplast thylakoid proteins.”  Jiang F.et.al.   11891220
[7] “Functional interaction of chloroplast SRP/FtsY with the ALB3 translocase in thylakoids: substrate not required.”  Moore M.et.al.   14517205
Structure:
5E4W     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MARVLVSSPS SFFGSPLIKP SSSLRHSGVG GGGTAQFLPY RSNNNKLFTT STTVRFSLNE 
61:	IPPFHGLDSS VDIGAIFTRA ESLLYTIADA AVVGADSVVT TDSSAVQKSG GWFGFISDAM 
121:	ELVLKILKDG LSAVHVPYAY GFAIILLTII VKAATYPLTK QQVESTLAMQ NLQPKIKAIQ 
181:	QRYAGNQERI QLETSRLYKQ AGVNPLAGCL PTLATIPVWI GLYQALSNVA NEGLFTEGFF 
241:	WIPSLGGPTS IAARQSGSGI SWLFPFVDGH PPLGWYDTVA YLVLPVLLIA SQYVSMEIMK 
301:	PPQTDDPAQK NTLLVFKFLP LMIGYFALSV PSGLSIYWLT NNVLSTAQQV YLRKLGGAKP 
361:	NMDENASKII SAGRAKRSIA QPDDAGERFR QLKEQEKRSK KNKAVAKDTV ELVEESQSES 
421:	EEGSDDEEEE AREGALASST TSKPLPEVGQ RRSKRSKRKR TV