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2.A.94 The Phosphate Permease (Pho1) Family

Pho1 of A. thaliana is a member of the PHO1 family (11 paralogues in A. thaliana). It functions in inorganic phosphate transport and homeostasis. Pho1 catalyzes efflux of phosphate from epidermal and cortical cells into the xylem (Quaghebeur and Rengel, 2004; Stefanovic et al., 2007). The SPX superfamily domain is an N-terminal soluble domain. These proteins belong to the EXS (Erd1/Xpr1/Syg1) superfamily. 

The generalized reaction catalyzed by Pho1 is:

Pi (cells) → Pi (xylem)

This family belongs to the IT Superfamily.


This family belongs to the: IT Superfamily.

References associated with 2.A.94 family:

Hamburger, D., E. Rezzonico, J. MacDonald-Comber Petétot, C. Somerville, and Y. Poirier. (2002). Identification and characterization of the Arabidopsis PHO1 gene involved in phosphate loading to the xylem. Plant Cell 14: 889-902. 11971143
Quaghebeur, M., and Z. Rengel. (2004). Arsenic uptake, translocation and speciation in pho1 and pho2 mutants of Arabidopsis thaliana. Physiol. Plant. 120: 280-286. 15032863
Stefanovic, A., C. Ribot, H. Rouached, Y. Wang, J. Chong, L. Belbahri, S. Delessert, and Y. Poirier. (2007). Members of the PHO1 gene family show limited functional redundancy in phosphate transfer to the shoot, and are regulated by phosphate deficiency via distinct pathways. Plant J. 50: 982-994. 17461783