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2.A.96.1.7
Ammonia transport outward protein 2, ATO2

Accession Number:P32907
Protein Name:Ammonia transport outward protein 2
Length:282
Molecular Weight:30701.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ammonia

Cross database links:

Genevestigator: P32907
eggNOG: COG1584
HEGENOM: HOG000224167
DIP: DIP-7904N
Entrez Gene ID: 855736   
Pfam: PF01184   
KEGG: sce:YNR002C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005739 C:mitochondrion
GO:0005886 C:plasma membrane
GO:0008519 F:ammonium transmembrane transporter activity
GO:0019740 P:nitrogen utilization

References (9)

[1] “An essential and specific subunit of RNA polymerase III (C) is encoded by gene RPC34 in Saccharomyces cerevisiae.”  Stettler S.et.al.   1400451
[2] “Organization of the centromeric region of chromosome XIV in Saccharomyces cerevisiae.”  Lalo D.et.al.   7941739
[3] “Twelve open reading frames revealed in the 23.6 kb segment flanking the centromere on the Saccharomyces cerevisiae chromosome XIV right arm.”  Verhasselt P.et.al.   7900425
[4] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.”  Philippsen P.et.al.   9169873
[5] “Ammonia pulses and metabolic oscillations guide yeast colony development.”  Palkova Z.et.al.   12429834
[6] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[7] “Association of putative ammonium exporters Ato with detergent-resistant compartments of plasma membrane during yeast colony development: pH affects Ato1p localisation in patches.”  Ricicova M.et.al.   17395151
[8] “Mutations at different sites in members of the Gpr1/Fun34/YaaH protein family cause hypersensitivity to acetic acid in Saccharomyces cerevisiae as well as in Yarrowia lipolytica.”  Gentsch M.et.al.   17233767
[9] “Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.”  Reinders J.et.al.   17761666

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSDREQSSGN TAFENPKALD SSEGEFISEN NDQSRHSQES ICKIYTAGKN NEYIYIGRQK 
61:	FLRDDLFEAF GGTLNPGLAP APVHKFANPA PLGLSGFALT TFVLSMFNAR AQGITIPNVV 
121:	VGCAMFYGGL VQLIAGIWEI ALENTFGGTA LCSFGGFWLS FGAIYIPWFG ILDAYKDKES 
181:	DLGNALGFYL LGWALFTFGL SVCTMKSTIM FFALFFLLAV TFLLLSIANF TGEVGVTRAG 
241:	GVLGVIVAFI AWYNAYAGIA TRQNSYIMVH PFALPSNDKV FF