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2.A.96.2.1
Ethanol-induced protein AlcS (6 TMSs.  May be distantly related to the second half (TMSs 7-12)) of APC family member, 3.A.3.3.4. This subfamily is absent from yeast and bacteria (Flipphi et al., 2006).

Accession Number:Q460G9
Protein Name:AlcS
Length:262
Molecular Weight:28014.00
Species:Emericella nidulans [162425]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Alcaligin

Cross database links:

RefSeq: XP_682250.1   
Entrez Gene ID: 2868276   
Pfam: PF01184   

Gene Ontology

GO:0016020 C:membrane

References (4)

[1] “Functional analysis of alcS, a gene of the alc cluster in Aspergillus nidulans.”  Flipphi M.et.al.   16531087
[2] “Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.”  Galagan J.E.et.al.   16372000
[3] “The 2008 update of the Aspergillus nidulans genome annotation: a community effort.”  Wortman J.R.et.al.   19146970
[4] “A newly identified gene cluster in Aspergillus nidulans comprises five novel genes localized in the alc region that are controlled both by the specific transactivator AlcR and the general carbon-catabolite repressor CreA.”  Fillinger S.et.al.   8736527

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTTEISNGEA KGHHLSTIPS SITLSAEQFE KLYLSPMMRQ QPSLARKVGN PTPLALGGFV 
61:	ITTTPLSCCL MAWRGSSGNG IAFIGPIIFL GGLLLLITSI LEFILGNTFP CVVFGTIGGF 
121:	WFAFAATMIP SFNAAAPYSS SATSTTAGLT SASFMNTYAF LFITMAVLML IFLLCATRTN 
181:	VVYTLIFLSL LLVFLLLSAG YWRLGEGDAA VGDRCIKGAG ASLFVASLLG FYLLIAQLFD 
241:	AVGLPITLPV GDMERFWPRS QK