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2.A.97.1.2
Mitochondrial distribution and morphology protein Mdm38p (Yol027c)

Accession Number:Q08179
Protein Name:Mitochondrial distribution and morphology protein 38
Length:573
Molecular Weight:65005.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1
Substrate Unknown

Cross database links:

Genevestigator: Q08179
eggNOG: fuNOG07700
HEGENOM: HBG395478
RefSeq: NP_014615.1   
Entrez Gene ID: 854130   
Pfam: PF07766   
KEGG: sce:YOL027C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0042802 F:identical protein binding
GO:0030007 P:cellular potassium ion homeostasis
GO:0006813 P:potassium ion transport
GO:0051204 P:protein insertion into mitochondrial membrane
GO:0015992 P:proton transport

References (6)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[2] “Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.”  Dimmer K.S.et.al.   11907266
[3] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095
[4] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[5] “The proteome of Saccharomyces cerevisiae mitochondria.”  Sickmann A.et.al.   14576278
[6] “The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome.”  Nowikovsky K.et.al.   15138253
Structure:
3SKQ     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLNFASRASC VTRRQASLYF VKNQGPRLIA STIPSCHWPL RAQGVQPNYP LSLRFYSTDK 
61:	SKSVTKPVAP TSTDAPAKPK ETLMVKVKHA LKHYANGTKL LGYEIKVSTK LLIKFAQGYE 
121:	LSRRERNQLR RTMGDVFRLI PFSAFLIIPF AELFLPFALK LFPNLLPSTY ESGKDKQAKR 
181:	NKLIEIRKKT SEFLHETLEE SNLITYNTIE NAEKKQKFLN FFRKLYSAKE GKIMTFQHDE 
241:	ISAIAQMFKN DSVLDNLSRP QLAAMSKFMS LRPFGNDNML RYQIRSKLKD IMNDDKTIDY 
301:	EGVESLSQEE LYQACVSRGM KAYGVSKEDL VDNLKVWLEL RLRQKIPSVL MVLSSTFTFG 
361:	GLPKENYSKA FSPLAEKKET KSKYDDLLDL YYDGILQVLS SIPDPVYNVA KLDVSESKSS 
421:	AAETEAEKQV AEKKIKTEEK PEETAIPKEE ATAKESVIAT TASAVTPKLV VVNEKAETAK 
481:	TEEISQEKEN AEPTDSAEAT EAEEKKTSDD NEFKLNVLKE QEELIKKEEE EAKQRASREH 
541:	VPDDINLDEE EEAKSVPPIP ADQAAKTFVI KKD