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2.B.21 The ortho-Phenylenediamine-bis-Urea Derivative Anion Transporter (oPDA-U) Family

Fluorinated ortho-phenylenediamine-bis-urea derivatives have been shown to function as highly effective transmembrane anion antiporters with the most active transporters rivalling the transport efficacy of the natural anion transporter, prodigiosin (2.B.20), for bicarbonate (Karagiannidis et al. 2014; Gale 2011).

References associated with 2.B.21 family:

Gale, P.A. (2011). From anion receptors to transporters. Acc Chem Res 44: 216-226. 21207951
Karagiannidis, L.E., C.J. Haynes, K.J. Holder, I.L. Kirby, S.J. Moore, N.J. Wells, and P.A. Gale. (2014). Highly effective yet simple transmembrane anion transporters based upon ortho-phenylenediamine bis-ureas. Chem Commun (Camb) 50: 12050-12053. 25178589