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3.A.1.103.9
ABC O-antigen lipopolysaccharide/polysaccharide export transporter, Wzm/Wzt of 253 aas and 6 TMSs (Wzm; also called AbcT3) and 396 aas and 0 TMSs (Wzt). The crystal structure is available (PDB 6AN7) (Bi et al. 2018) for the Wzm-Wzt homologue from Aquifex aeolicus in an open conformation. The transporter forms a transmembrane channel that is sufficiently wide to accommodate a linear polysaccharide. Its nucleotide-binding domain and a periplasmic extension form 'gate helices' at the cytosolic and periplasmic membrane interfaces that probably serve as substrate entry and exit points (Bi et al. 2018).

Accession Number:O67182
Protein Name:Transport permease protein
Length:256
Molecular Weight:30005.00
Species:Aquifex aeolicus (strain VF5) [224324]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

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FASTA formatted sequence
1:	MNLSLILELV RQEIKNRYAD TVLGIWWAFL WPILLVLIYT LIFSHLIGAK LGHENTVYAY 
61:	SIYLSSGIFP WFFFSNSLSR ITGIFTEKKF LFTKIPIRLE VFPVVVIISE LINYLIGISL 
121:	VTLISFITLG FEGIKYFYLF PVALYLMIVY SFSIGMVLGT LNVFFRDIKE IIGVFLQIFF 
181:	WFTPIVYTLD ILPPFVKKLI YYNPMYPVVS IHHLVFVNYL DLHLYSLLGF LLASPLVFFV 
241:	SYYFFKKLEK DIKDFA