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3.A.1.109.8
Leukotoxin export protein of 707 aas, LtxB (has a fused M-C structure with 6 TMSs) (Guthmiller et al. 1995). Functions with the MFP, LtxD (TC# 8.A.1.3.4) and the TolC-like protein, TdeA (TC# 1.B.17.3.11).

Accession Number:P23702
Protein Name:Leukotoxin export ATP-binding protein LtxB
Length:707
Molecular Weight:79579.00
Species:Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) [714]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Leukotoxin

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDSQKNTNLA LQALEVLAQY HNISINPEEI KHKFDIDGHG LNQTKWLLAA KSLGLKVRTA 
61:	NKTVDRLPFL HLPALAWRDD GEHFILLKID QETDRYLIFD LIQKNPIVLD KNEFEERYQS 
121:	KVILIASRAS IVGNLAKFDF TWFIPAVIKY RKIFIETLIV SIFLQIFALI TPLFFQVVMD 
181:	KVLVHRGFST LNVITVALAI VVLFEIILGG LRTYVFAHST SRIDVELGAR LFRHLLALPI 
241:	SYFEARRVGD TVARVRELDQ IRNFLTGQAL TSILDLLFSF IFFAVMWYYS PKLTLVVLGS 
301:	LPCYVIWSVF ISPILRRRLD DKFARNADNQ SFLVESVTAI NTIKAMAISP QMTNIWDKQL 
361:	ASYVAVSFKV TVLATIGQQG IQLIQKAVMV INLWLGAHLV ISGDLSIGQL IAFNMLAGQI 
421:	ISPVIRLAQI WQDFQQVGIS VTRLGDVLNS PTENNTASVS LPEIQGEISF RNIKFRYKPD 
481:	SPMILNNINL DISQGEVIGI VGRSGSGKST LTKLIQRFYI PEQGQVLIDG HDLALADPNW 
541:	LRRQVGVVLQ DNVLLNRSIR ENIALTNPGM PMEKVIAAAK LAGAHDFISE LREGYNTVVG 
601:	EQGAGLSGGQ RQRIAIARAL VNNPRILIFD EATSALDYES ENIIMHNMHK ICQNRTVLII 
661:	AHRLSTVKNA DRIIVMDKGE IIEQGKHQEL LKDEKGLYSY LHQLQVN