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3.A.1.111.2
Subtilin (toxic peptide) exporter

Accession Number:P33116
Protein Name:SPAT aka SpaB aka SPAY
Length:614
Molecular Weight:71188.00
Species:Bacillus subtilis [1423]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Subtilin

Cross database links:

Pfam: PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0043213 P:bacteriocin transport
GO:0055085 P:transmembrane transport

References (2)

[1] “Analysis of genes involved in biosynthesis of the lantibiotic subtilin.”  Klein C.et.al.   1539969
[2] “The subtilin gene of Bacillus subtilis ATCC 6633 is encoded in an operon that contains a homolog of the hemolysin B transport protein.”  Chung Y.J.et.al.   1735728

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MEVKEQLKLK ELLFIMKQMP KTFKLIFTLE RSLFLKLIRF SIITGILPIV SLYISQELIN 
61:	SLVTIRKEVS IVITIFLTYL GVSFFSELIS QISEFYNGKF QLNIGYKLNY KVMKKSSNLA 
121:	LKDFENPEIY DKLERVTKEI SYKPYQIIQA IITMTTSFVT LLSSIAFLMS WNPKVSLLLL 
181:	VIPVISLFYF LKIGQEEFFI HWKRAGKERK SWYISYILTH DFSFKELKLY NLKDYLLNKY 
241:	WDIKKSFIEQ DTKILRKKTL LNLIYEIAVQ LVGAVIIFIA IMSAFAGKIM VGNVMSYIRS 
301:	VSLVQNHSQS IMTSIYSIYN SNLYMNQLYE FLELKEEKSQ GHKKPIVEPI HSVVFQNVSF 
361:	IYPNQGEQTL KHINVSLHKG ERVAIVGPNG SGKKTFIKLL TGLYEVHEGD ILINGINIKE 
421:	LDMDSYMNQI AALFQDFMKY EMTLKENIGF GQIDKLHQTN KMHEVLDIVR ADFLKSHSSY 
481:	QFDTQLGLWF DEGRQLSGGQ WQKIALARAY FREASLYILD EPSSALDPIA EKETFDTFFS 
541:	LSKDKIGIFI SHRLVAAKLA DRIIVMDKGE IVGIGTHEEL LKTCPLYKKM DESENYMNPL 
601:	EEEGSKWKEA LYQG