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3.A.1.112.8
Mesenterici Y105 (bacteriocin) ABC exporter and porcessing protease, MesD(E) of 722 aas and 6 TMSs (MesD) (Fremaux et al. 1995). MesDE can transport and catalyze maturation of the two pre-bacteriocins, mesentericin Y105 and B105 (Aucher et al. 2004).  Hydrophobic conserved amino acyl residues and the C-terminal GG doublet of the leader peptide of pre-mesentericin Y105 are critical for optimal secretion (Aucher et al. 2005).  MesE has TC# 8.A.1.4.1.

Accession Number:Q10418
Protein Name:Mesentericin-Y105 transport/processing ATP-binding protein MesD
Length:722
Molecular Weight:79916.00
Species:Leuconostoc mesenteroides [1245]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Mesentericin Y105, Mesentericin B105

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVKTPMFHKK IDYISQVDER DCGVAALAMI LAHYKTRLSL AKLRDLAKTD MEGTTALGIV 
61:	KAANALDFET MPIQADLSLF DKKDLPYPFI AHVIKEGKYP HYYVVYGMKG DQLLIADPDN 
121:	TVGKTKMTKA HFNEEWTGVS IFIAPNPTYK PTKEKKRSLT SFIPVITRQK LLVINIVIAA 
181:	LLVTLVSILG SYYLQGIIDT YIPNNMKNTL GIVSLGLIFA YVIQQLLSYA RDYLLIVMGQ 
241:	RLSIDIILSY IKHIFELPMS FFATRRTGEI VSRFTDANAI IEALASTMLS VFLDLGILVI 
301:	VGTVLVVQNS TLFLISLIAI PAYALVVWLF MRPFSKMNND QMQAGSMLSS SIIEDINGVE 
361:	TIKALNSEAT AYHKIDHEFV TYLEKSFVYA KTEAVQNAIK SLLQLSLNVV ILWVGAQLVM 
421:	TNKISVGQLI TYNALLGFFT DPLQNIINLQ TKLQQASVAN NRLNEVYLVD SEFKDSHQMT 
481:	EKITPNSSLV ADHITYKYGF GAPAIDDVSL TITAGEKIAL VGISGSGKST LVKLLVNFFQ 
541:	PESGTISLGP TPLANLDKHE LRGHINYLPQ EPFIFSGSIM ENLLLGAKPG TTQEDIIRAV 
601:	EIAEIKDDIE KMSQGFGTEL AESGNISGGQ KQRIALARAI LVDSPVLILD ESTSNLDVLT 
661:	EKKIIDNLMK LTEKTIIFVA HRLTISQRVD RILTMQSGKI IEDGTHDTLL KAGGFYASLF 
721:	NH