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3.A.1.123.1
Pep5 lantibiotic exporter, PepT

Accession Number:Q54121
Protein Name:PepT
Length:571
Molecular Weight:64178.00
Species:Staphylococcus epidermidis [1282]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Lantibiotics

Cross database links:

Pfam: PF00664    PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (1)

[1] “Nucleotide sequence of the lantibiotic Pep5 biosynthetic gene cluster and functional analysis of PepP and PepC. Evidence for a role of PepC in thioether formation.”  Meyer C.et.al.   7556197

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MKKENPLFFL FSKIKWPKSL FIIAIIISSI GSITEIIVPL LTGNLIDLLV KQTLELKFIV 
61:	FLILMFLLDA IFSGLGLFLL IKVGEKIIYS IRSILWKHIL FLNTSFFDKN ESGQLISRIT 
121:	DDTSLINNFI SQKLPAIIPS FITLIGSITM LFIMDWKMTL LTFIIIPIFL MVIIPLGNII 
181:	EKLSFKTQQK VADFTGTIGR VISAIRLVKI STNEEFELNN TKEKLSSIYK LNIKHAKIIA 
241:	ILQPFTSILL LVMIGIILSY GGYRIAVGAI TSGTLVSMIF YVIQLSSPIS EISTLITEYK 
301:	SSKGASKRIY GILNEPVEEN KVNLENIPQN KELIFNSVYF SYDSKNVLEN VSFAVPINKK 
361:	TAIVGPSGSG KSTILNLISR LYKADSGGIY YGGHSIYDID LKKWRIKLGY VMQNNIMMNG 
421:	SIRDNILYGV SNNISDDELE YYSILANSHD FISNLPHQYD SQIGESGIKL SGGQKQRINI 
481:	ARNLIKNPDI LLLDEATASL DSESEKKIQN ALNNLFQNRT TIIIGIAYRL LRTADQIIFL 
541:	DNGKITGIGT HHYLIKNHNK YNTFVSNQSI N