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3.A.1.201.25
MDR transporter, Crmdr1 of 1266 aas and 12 TMSs.  Crmdr1 is constitutively expressed in the root, stem and leaf with lower expression in leaf. It has two transmembrane domains (TMDs) and two nucleotide binding domains (NBDs) arranging in "TMD1-NBD1-TMD2-NBD2" direction (Jin et al. 2007).  

Accession Number:A5X7X7
Protein Name:MDR-like ABC transporter
Length:1266
Molecular Weight:137063.00
Species:Catharanthus roseus (Madagascar periwinkle) [4058]
Number of TMSs:12
Substrate drugs

Cross database links:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKSEDGAPN SPSSSKDNEK VPFLKLFSFA DGMDIALMII GTLGGIGNGL AQPIMTVILG 
61:	QLINTFGTNI YDKSEILHQV GQVSLKYVYL AIGAGMASFL QMSCWMVTGE RQATRIRGLY 
121:	LKTILRQDIG FFDTETSTGE VIGRMSGDTI LIQEAMGEKV GKFIQFSSTF IGGFLIAFIK 
181:	GWLLALVLTA CLPLLVATGA VMSLFMSKMA SQGQVAYAEA GNVLEQTVGG IRTVASFTGE 
241:	KLAIQKYNNK LKVAYRTTVK QGFASGAGFG TLLLVVFCIY GLAIYYGSRL IIEKGYNGGR 
301:	VINVMMAIMM GGMSLGQTSP SLSAFAAGQA AAYKMFETIK RKPQIDAYDT SGIVLEDIKG 
361:	EIELKDVYFR YPARPEVQIF SGFSLYVPSG TTAALVGQSG SGKSTVISLL ERFYDPEAGE 
421:	VLIDGVNLKK MRLRWLREQL GLVSQEPILF ATTIKENILY GKSNATDSEI RTAIQLANAA 
481:	KFIDKLPQGL DTMVGEHGTQ LSGGQKQRIA IARAILKNPR ILLLDEATSA LDAESERIVQ 
541:	DALDNVMSNR TTVVVAHRLS TIRNAHLIAV VQSGKLVEQG THAELIKDPN GAYSQLIRMQ 
601:	QGSKDTEDSR LLDVEKLDAE IDADETLMKS PSQRMSLRRS SSRGSSRKSF TFNYGIPGLV 
661:	EIHETEVGED EAEGDNTDIV SHKKVSFKRL AILNKPEIPQ LLLGSVAAII HGVIFPVFGL 
721:	LLSKSVRIMY EPPHQLRKDA RFWCLMYVGL GIITLLVLPL QNYFFGIAGG KLIERIRSLS 
781:	FEKVVHQEIS WFDDSKNSSG AVGARLSSDA STLRSLVGDA LALVVQNIAT VAAGLVISFT 
841:	ANWILALIIL AVLPLVGLQG FLQMKFYKGF SADAKVMYEE ASQVANDAVG SIRTVASFCA 
901:	EEKVMEMYQR KCEGPVKQGV RLGMVSGAGL GIGNGANYCA SAFCFYIGAV LVFHGKATFG 
961:	EVFRVFFALT MSAMGVSQAM ALAPDVNKTK QSAASVFEIL DAKPKIDSSS NKGQTLASVK 
1021:	GDIELQHISF KYPTRPDIQI FKGLCLSIPC GKTVALVGES GSGKSTVISL IERFYDPDSG 
1081:	NIYLDGVELQ KLKISWLRQQ MGLVSQEPVL FNESIRDNIA YGKQGNATED EIIAATKASN 
1141:	AHSFISSLPN GYDTSVGERG VQLSGGQKQR IAIARAILKD PRILLLDEAT SALDAESERI 
1201:	VQDALDKVMV NRTTVVVAHR LSTIKGADVI AVVKNGVISE KGRHDELMKM ENGVYASLVS 
1261:	LQSSAA