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3.A.1.203.12
ABC transporter, BclA, of 586 aas and 6 TMSs in a 2 + 2 + 2 arrangement in the N-terminus and the ABC domain in the C-terminus.  It is a peptide transprter required for bacteroid differentiation.  It catalyzes import of peptides called nodule-specific cysteine-rich (NCR) peptides in the symbiotic nodule cells which house the bacteroids. NCR peptides are related to antimicrobial peptides of innate immunity, but they induce the endosymbionts into a differentiated, enlarged, and polyploid state (Guefrachi et al. 2015). BclA is required for the formation of differentiated and functional bacteroids in the nodules of the NCR peptide-producing Aeschynomene legumes. BclA catalyzes import of NCR peptides and provides protection against the antimicrobial activity of these peptides. Moreover, BclA can complement the role of the related BacA transporter of Sinorhizobium meliloti, which has a similar symbiotic function in the interaction with Medicago legumes (Guefrachi et al. 2015).

Accession Number:H0RSU6
Protein Name:Putative ABC transporter
Length:586
Molecular Weight:65470.00
Species:Bradyrhizobium sp. ORS 285 [115808]
Number of TMSs:6
Substrate

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FASTA formatted sequence
1:	MNNLRSTLAI VWRIAIPYFR SEDKVAGRIL LAAVIAIELA LVAIDVLVNQ WQNRFYNALQ 
61:	EYNWNSFIWE IGVFAVLATT FIVLAIYQLY LNQWLQIRWR RWLTETYMRH WLSNANHYRM 
121:	QLKGDAADNP DQRIADDVKQ FVEQTLYITV NLLSSVVTLA SFVVILWGLS EAAPLTLFGM 
181:	EYNIPGYLVW AALIYAIAGT ALTHWIGSPL VNLNFEQQRF EADFRFNLVR VRENSEQIAL 
241:	LRGESAEHDL LSNRYGRVVQ NWYQIMTRTK RLTAVTSGYS QVATIFPYVI VAPAYFAKKV 
301:	QLGGMMQTAS AFSSVQRALS FFVNTYRTLA DWRSTVARLD GFEMSIASAV TLSGEPQTID 
361:	VVSHAGDSIE LAQLLLKLPN GLPLIAADGF SFKSNQSMLL TGPSGAGKST LFRAIAGVWP 
421:	FGSGAISVPG HAKLMMLPQR PYFPIGALQT AVVYPAAPDA FSPEQVKDAL VAVGLPLLAE 
481:	RLDEEAHWNR MLSLGEQQRL GIARALLHQP QFLFLDEATA SLDEPSEARL YRAIAERLPQ 
541:	TTVVSIGHRS TLHDFHDRKV ELVRDGDRFS LRPTGQAADA PAGGAE