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3.A.1.203.15
ABCD1 transporter of 766 aas and 6 TMSs. Similar to human patients with X-linked adrenoleukodystrophy (ALD), zebrafish abcd1 mutants have elevated very long chain fatty acid levels, and CNS development was disrupted, with hypomyelination in the spinal cord, abnormal patterning, decreased numbers of oligodendrocytes, and impaired motor function followed by increased cell death (Strachan et al. 2017). Expression of human ABCD1 in zebrafish oligodendrocytes rescued apoptosis in the abcd1 mutant (Strachan et al. 2017).

Accession Number:F1RBC8
Protein Name:ATP-binding cassette, sub-family D (ALD), member 1
Length:766
Molecular Weight:86594.00
Species:Danio rerio (Zebrafish) [7955]
Number of TMSs:4
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSVYSKLPSQ LKKPLVKKAV VLLIALYGVK KLSPYFFGKL KGRTSKQVKG ADPLTSNGEP 
61:	LVEAARKRKR SPAVNREFFD RLIRLLKILF PRLFCKELGL LGFHSLALIS RTFLSIYVAN 
121:	LDGQIVKTIV KKDPRAFVVE LTKWLLIAIP ATFVNSAIRY LEGQLTLAFR TRLVTHAYML 
181:	YFSDQTYYRV SNMDGRLANP DQSLTEDVVM FAASVAHLYS NLTKPILDVV VTCYTLIKTA 
241:	ESKGANTTWP SVIAGIVVAL TAKVLRAFSP RFGKLVAEEA RRKGDLRYMH SRIIANSEEI 
301:	AFYGGHKIEM LQLQRSYNSL SRQINLILFK RLWYVMLEQF LMKYLWSASG LVMVAVPIIT 
361:	ATGYSKYDSE DVKQAALDMK EEDLVSERTQ AFTTARSLLN AAADAVERIM VSYKEVTELA 
421:	GYTARVYEMF EVFEDVRDGV YRRSATEVKP EETGAPQNVT HGMRVEGPLQ IRGQVIDVEQ 
481:	GIKCENLPII TPTGDVVVSS LNMQVDEGMH LLITGPNGCG KSSLFRILSG LWPVYSGVLY 
541:	KPSPDHMFYI PQRPYMSVGT LRDQVIYPHS VQEMQEKGIT DRQLEEILQT VSLRYILERE 
601:	GGWDAVSDWK DVLSGGEKQR MGMARMFYHK PQYALLDECT SAVSIDVEGK IFEAAKDAGI 
661:	SLLSITHRPS LWKYHSHLLQ FDGEGGWRFE KLDASTRISL QDEKIRLETQ LSGIPKMQQR 
721:	LTELCRILGE DSSLPTPGDE EEDEEEDEKQ TERDVQSAGK EKDLME