TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.204.7
Multidrug resistance efflux pump, AbcG6, causes camptothecin-resistant parasites (Bosedasgupta et al., 2008)

Accession Number:A8WEV1
Protein Name:AbcG6
Length:668
Molecular Weight:72723.00
Species:Leishmania donovani [5661]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell junction1 / Multi-pass membrane protein2
Substrate drugs, camptothecin

Cross database links:

Pfam: PF01061    PF00005   

Gene Ontology

GO:0016020 C:membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSSPAPPTDR ADAGLLHHLP HSPPESPESS PPPPASSHRT AVLTWEDVSY TVSGADEGDT 
61:	RILVRHVSGY VQSGEMLAVL GPSGAGKTTL LDILAQRKMK SKGDITGRIM LNGEPVEPAA 
121:	FQLCSGYVQQ EDIMHSYVTV EEVVRFSATL RTSPTISEEA LESRVSQVLR QLGIYHVRHS 
181:	CIGSALMRGI SGGERKRCAV AAEMVTLPSL LFLDEPTTGL DTFTALHLLT LLRSLSRSGV 
241:	AVVFSIHQPR SRIYEAFDRV LLLNGFGEEA YFGPAADAVQ FLAEIGLSSG CSSNPADYLI 
301:	DAVSVLPVEE AWLSEEAQQS AAVEAATDGN QLRLPSPAPT QGRDIAAAFA SLRLADVMRQ 
361:	IDELQRSSRA ATAALAETGS PVRAYPRSWT TQVRCIAMRC LRNRRRDPVA TYVSVTSAIV 
421:	FAFLTGTIYY QIGNSQDSIR SRMGVLFFIM MISTFSSLGS LEMFLTDRAI YAREHRNGMY 
481:	STSAYYVGKF IQDAPIVVAI NFLFNLVVYL LVGLQGTVAK FLIFDSVGAL VTLNSYALCL 
541:	LMSNLSKDYA TGNIITSLLL VLYLLPTAGM LVSLNSIPFM WRWIKHISFA RFAFSVMVAN 
601:	EFDGLTFVCD PVPSDIASCI TSGTTYAASQ GMYAKDIRSH MLVVALSMAV YLVLGYLVLR 
661:	GWRSTEGK