TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.205.12
The plasma membrane Pdr10, a negative regulator for incorporation of Pdr12 (TC# 3.A.1.205.3) into detergent-resistant membranes, a novel role for members of the ABC transporter superfamily (Rockwell et al., 2009) (most like 3.A.1.205.1; 67% identity).

Accession Number:P51533
Protein Name:ATP-dependent permease PDR10
Length:1564
Molecular Weight:176461.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:15
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P51533
eggNOG: fuNOG04532
HEGENOM: HBG323792
RefSeq: NP_014973.1   
Entrez Gene ID: 854506   
Pfam: PF01061    PF00005    PF06422   
KEGG: sce:YOR328W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0006855 P:drug transmembrane transport

References (2)

[1] “Sequence of 29 kb around the PDR10 locus on the right arm of Saccharomyces cerevisiae chromosome XV: similarity to part of chromosome I.”  Parle-McDermott A.G.et.al.   8896263
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLQAPSSSNS GLNQGNAAPD GPPNETQPYE GLDAAAQEEI KELARTLTSQ SSLLSQEKRI 
61:	TGTGDPNTLT AASSSSLSRS IFASDIKGVN PILLDVNDPD YDETLDPRSE NFSSVRWVRN 
121:	MAQICENDSD FYKPFSLGCA WKDLSASGDS ADITYQGTFG NMPIKYLKMS WRCISRRLFH 
181:	RTHGKSEDND SGFQILKPMD GCINPGELLV VLGRPGAGCT TLLKSISVNT HGFKISPDTI 
241:	ITYNGFSNKE IKNHYRGEVV YNAESDIHIP HLTVFQTLYT VARLKTPRNR IKGVDRDTFA 
301:	KHMTEVAMAT YGLSHTADTK VGNDFVRGVS GGERKRVSIA EVSICGSKFQ CWDNATRGLD 
361:	SATALEFIKA LKTQATITKS AATVAIYQCS KDAYDLFDKV CVLYDGYQIF FGPSKQAKKY 
421:	FQRMGYVCPE RQTTADYLTS ITSPSERIKD KDMVKHGIMI PQTAYEMNQY WIQSEEYKQL 
481:	QVQVNKHLDT DSSQQREQIK NAHIAKQSKR ARPSSPYTVS FFLQVKYILI RDIWRIKNDP 
541:	SIQLFTVLSH AAMALILGSM FYEVMLSTTT TTFYYRGAAI FFAILFNAFS SLLEIFSLYE 
601:	TRPITEKHKT YSLYRPSADA FASTFSDVPT KLATAVTFNI PYYFLINLKR DAGAFFFYFL 
661:	INIITVFAMS HLFRCIGSVS KTLPQAMVPA SVLLLAFAMY TGFAIPRVQM LGWSKWISYI 
721:	NPLSYLFESL MINEFHGRNF PCAQYIPSGP NYVNATGDEV TCSALGSIPG NNYVSGDDFI 
781:	QTNYGYRHKN KWRSVGIGLA YIIFFLFLYL FFCEYNEGAK QNGEMLVFPH SVVKKMKKKG 
841:	IVSEKKKKNQ PTLSTSDAEK DVEMNNNSSA TDSRFLRDSD AAIMGNDKTV AKEHYSSPSS 
901:	SASQSNSFSK SDDIELSKSQ AIFHWKNLCY DIPIKNGKRR ILDNVDGWVK PGTLTALIGA 
961:	SGAGKTTLLD CLAERTTMGL ITGDVFVDGR PRDQSFPRSI GYCQQQDLHL KTATVRESLR 
1021:	FSAYLRQADD VSIEEKDKYV EEVIEVLEMK LYADAIVGVP GEGLNVEQRK RLTIGVELAA 
1081:	KPKLLVFLDE PTSGLDSQTA WSTCQLMKKL ASRGQAILCT IHQPSALLMQ EFDRLLFLQE 
1141:	GGQTVYFGEL GKGCKTMINY FEAHGAHKCP PDANPAEWML EIVGAAPGTH ASQDYFAIWR 
1201:	DSEEYREMQK ELDWMERELP KRTEGSSNEE QKEFATSTLY QIKLVSYRLF HQYWRTPFYL 
1261:	WSKFFSTIVS ELFIGFTFFK ANTSLQGLQN QMLAIFMFTV VFNPILQQYL PLFVQQRELY 
1321:	EARERPSRTF SWKAFIVSQI LVEIPWNLLA GTIAFFVYYY PVGFYRNASY ANQLHERGAL 
1381:	FWLFACAFYV YISSMGVLVI SCIEIAENAA NLASLFFIMS LSFCGVLATP NILPRFWIFM 
1441:	YRVSPLTYLI DALLSVGLAN ASVVCSSNEL LKIVPPSGMT CSEYMEPYMQ STGTGYLLDG 
1501:	SSETECHFCQ FSSTNDYLAT VSSSYSRRWM NYGIFSAYIV FDYCAAIFLY WLVRVPKKSK 
1561:	KLKK