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3.A.1.205.25
Plasma membrane ABCG1 or PDR1a of 1434 aas and 12 TMSs.  85% identical to TC# 3.A.1.205.21. PDR1 secretes plastid-produced diterpene(s) that are the antimicrobial compounds active in preinvasion defense, as well as the sesquiterpenoid, capsidiol, the major phytoalexin produced by Nicotiana and Capsicum species. Capsidiol is produced in plant tissues attacked by pathogens and plays a major role in postinvasion defense by inhibiting pathogen growth (Shibata et al. 2016).   This protein and ABCG2/PDR2, a close paralogue, export the same compounds and are essential for resistance to the potato late blight pathogen Phytophthora infestans. Thus, ABCG1/2 are involved in the export of both antimicrobial diterpene(s) for preinvasion defense and capsidiol for postinvasion defense against P. infestans.

Accession Number:BAR94041
Protein Name:BAR94041.1 PDR-type ACB transporter [Nicotiana benthamiana]
Length:1435
Molecular Weight:
Species:Nicotiana benthamiana [4100]
Number of TMSs:13
Substrate diterpenes, capsidiol, sesquiterpenoids

Cross database links:

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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEPANLSNLR GSSLRGSMRG SLRANSNSIW RNNGVEIFSR SSRDEDDEEA LKWAALEKLP 
61:	TFDRLRKGLL FGSQGAAAEV DINDLGFQER KNLLERLVKV ADEDNEKFLL KLKNRIDRVG 
121:	IDLPTIEVRY EHLNIDADAY VGSRGLPTFM NFMTNFVETL LNSLHILPSR KRQLTILKDI 
181:	SGIIKPCRMT LLLGPPSSGK TTLLLALAGK LDPALKVTGK VSYNGHELHE FVPQRTAAYI 
241:	SQHDLHIGEM TVRETLEFSA RCQGVGSRFE MLAELSRREK AANIKPDADI DVYMKAAATE 
301:	GQEANVVTDY VLKILGLDIC ADTMVGDDMI RGISGGQKKR VTTGEMLVGP SKALFMDEIS 
361:	TGLDSSTTYS IVNSLRQSVQ ILKGTAVISL LQPAPETYNL FDDIILLSDG YIVYQGPRDD 
421:	VLEFFESMGF KCPHRKGVAD FLQEVTSKKD QQQYWSKRNE PYRFITSKEF AEAYQSFHVG 
481:	RKLGDELATP FDKTKCHPAA LTNEKYGIGK KELLKVCTER ELLLMKRNSF VYMFKFSQLT 
541:	IMALITMTLF FRTEMPRDTT DDGAIYAGAL FFVVIMIMFN GMSELAMTIF KLPVFYKQRD 
601:	LLFFPSWAYA IPSWILKIPV TLVEVGLWVI LTYYVIGFDP NITRFLKQFL LLIVVNQMAS 
661:	GLFRFIGAVG RTMGVASTFG SFALLLQFAL GGFVLSRDDV KSWWIWGYWT SPMMYSVNSI 
721:	LVNEFDGKKW NHIVPGGNET LGATVVKSRG FFPEAYWYWI GVGALVGFTV VFNFCYSVAL 
781:	AYLNPFDKPQ AVLAEDGENA ENVEVSSQIT STDGGDSISE SQNNKKGMVL PFEPHSITFD 
841:	DVVYSVDMPQ EMKEQGAGQD RLVLLKGVSG AFRPGVLTAL MGVSGAGKTT LMDVLAGRKT 
901:	GGYIDGEIKI SGYPKKQETF ARISGYCEQN DIHSPYVTVY ESLVYSAWLR LPQDVDEKTR 
961:	KMFVDEVMEL VELGPLRSAL VGLPGVNGLS TEQRKRLTIA VELVANPSII FMDEPTSGLD 
1021:	ARAAAIVMRT VRNTVDTGRT VVCTIHQPSI DIFEAFDELF LMKRGGQEIY VGPLGRHSCH 
1081:	LIKYFESNPG VAKIKEGYNP ATWMLEVTAS AQEMLLGVDF TEVYKNSDLY RSNKALISEL 
1141:	GVPRPGSKDL HFETQYSQSF WTQCMACLWK QHWSYWRNPA YTAVRFIFTT FIALIFGTMF 
1201:	WDLGTKVSES QDLLNAMGSM YAAVLFLGVQ NASSVQPVVA VERTVFYRER AAGMYSAIPY 
1261:	AFGQVAIEIP YIFVQSVFYG IIVYAMIGFE WDVGKFFWYL FIMFFTLLYF TFYGMMSVAV 
1321:	TPNQNVASIV AAFFYGVWNL FSGFIIPRPR MPVWWRWYYW ANPVAWTLYG LVASQFGDIQ 
1381:	TKLSDNETVK QFLRRFFGFR HDFLGVVAAV LSAYVFVFAF TFAFAIKAFN FQRR