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3.A.1.208.19
The possible HCO3- transporter, HLA3 (Duanmu et al., 2009).  Activation of HLA3 expression in high CO2 acclimated cells, where HLA3 is not expressed, resulted in increased Ci accumulation and Ci-dependent photosynthetic O2 evolution specifically in very low CO2 concentrations, which confirms that HLA3 is indeed involved in Ci uptake.  It also suggests that HLA3 is mainly associated with HCO3- transport in very low CO2 concentrations, conditions in which active CO2 uptake is limited (Gao et al. 2015).

Accession Number:A8I268
Protein Name:ABC transporter
Length:1082
Molecular Weight:119705.00
Species:Chlamydomonas reinhardtii [3055]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate bicarbonate

Cross database links:

RefSeq: XP_001700040.1   
Entrez Gene ID: 5725590   
Pfam: PF00664    PF00005   
KEGG: cre:CHLREDRAFT_   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (1)

[1] “The Chlamydomonas genome reveals the evolution of key animal and plant functions.”  Merchant S.S.et.al.   17932292

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MLPGLGVILL VLPMQYYFGY KIVQIKLQNA KHVALRSAIM QEVLPAIKLV KYYAWEQFFE 
61:	NQISKVRREE IRLNFWNCVM KVINVACVFC VPPMTAFVIF TTYEFQRARL VSSVAFTTLS 
121:	LFNILRFPLV VLPKALRAVS EANASLQRLE AYLLEEVPSG TAAVKTPKNA PPGAVIENGV 
181:	FHHPSNPNWH LHVPKFEVKP GQVVAVVGRI AAGKSSLVQA ILGNMVKEHG SFNVGGRISY 
241:	VPQNPWLQNL SLRDNVLFGE QFDENKYTDV IESCALTLDL QILSNGDQSK AGIRGVNFSG 
301:	GQRQRVNLAR CAYADADLVL LDNALSAVDH HTAHHIFDKC IKGLFSDKAV VLVTHQIEFM 
361:	PRCDNVAIMD EGRCLYFGKW NEEAQHLLGK LLPITHLLHA AGSQEAPPAP KKKAEDKAGP 
421:	QKSQSLQLTL APTSIGKPTE KPKDVQKLTA YQAALIYTWY GNLFLVGVCF FFFLAAQCSR 
481:	QISDFWVRWW VNDEYKKFPV KGEQDSAATT FYCLIYLLLV GLFYIFMIFR GATFLWWVLK 
541:	SSETIRRKAL HNVLNAPMGF FLVTPVGDLL LNFTKDQDIM DENLPDAVHF MGIYGLILLA 
601:	TTITVSVTIN FFAAFTGALI IMTLIMLSIY LPAATALKKA RAVSGGMLVG LVAEVLEGLG 
661:	VVQAFNKQEY FIEEAARRTN ITNSAVFNAE ALNLWLAFWC DFIGACLVGV VSAFAVGMAK 
721:	DLGGATVGLA FSNIIQMLVF YTWVVRFISE SISLFNSVEG MAYLADYVPH DGVFYDQRQK 
781:	DGVAKQIVLP DGNIVPAASK VQVVVDDAAL ARWPATGNIR FEDVWMQYRL DAPWALKGVT 
841:	FKINDGEKVG AVGRTGSGKS TTLLALYRMF ELGKGRILVD GVDIATLSLK RLRTGLSIIP 
901:	QEPVMFTGTV RSNLDPFGEF KDDAILWEVL KKVGLEDQAQ HAGGLDGQVD GTGGKAWSLG 
961:	QMQLVCLARA ALRAVPILCL DEATAAMDPH TEAIVQQTIK KVFDDRTTIT IAHRLDTIIE 
1021:	SDKIIVMEQG SLMEYESPSK LLANRDSMFS KLVDKTGPAA AAALRKMAED FWSTRSAQGR 
1081:	NQ