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3.A.1.208.22
California mussel ABCC/MRP-type multixenobiotic resistance efflux pump (Luckenbach and Epel, 2008).

Accession Number:B2WTI0
Protein Name:ABCC/MRP-like protein
Length:1498
Molecular Weight:169312.00
Species:Mytilus californianus (California mussel) [6549]
Number of TMSs:14
Substrate xenobiotics

Cross database links:

Pfam: PF00664    PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane movement of substances

References (1)

[1] “ABCB- and ABCC-type transporters confer multixenobiotic resistance and form an environment-tissue barrier in bivalve gills.”  Luckenbach T.et.al.   18401003

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MDNSLSVCNT QLSVQDSVTL VEGSYLSQWT PVLFVLAAPF HFLYFKRNFQ ASVVQYKFIL 
61:	AVFITLIGTL RISIGLRDIH DILFGEKSPD GLILSISIVL TTIIIQDESH KTQMKKKRKY 
121:	RFFRIFGLFC SFGISSAYII HKRTDTTVDN KWELQLIEWT TQLYCVLISV YLIESVILVL 
181:	KQVLGTDQSF QKGNADKDVS PEIKASYLSQ LTWSWVTPLV LHGYKHNLEQ SDLWPLTPGN 
241:	VSTNIIPIFE KYWEEEVEKA TRERQSQEKR KIQTTTNNVE KQIKANLLNC IIRASGPALL 
301:	LSAFYKLLYH FAEFAFPYIL RLLIGITKDR KEDIWKGYIL AILMFSVTIF KSVVLNLHIK 
361:	ETQEAGRSNW VALTAVIYKK TLRLTNAAKQ DSTVGEIINL MSVDAEKIGN CVWSLNEVWA 
421:	VPLLFSMAFY FLWQTLGSSV FVGLIIVLLL VPVNFVLMRK SKQLQLESMD LKDARIKKMN 
481:	EVLNGIKVLK MYAWEECFEK CILKIRDQEL HILAKREGIQ NWMHVIWATT PFTISLCTFG 
541:	AYVFMDVNNV MSAEKVFVSL SLFNILQYSL HLVPHVINYF IQTAVSLKRI QNFLNNEELD 
601:	TSIITRNTDS EYGITVEDGT FVWDTAMEPT LKNIRFKIPE GLLVAIVGSV GAGKSSLLSA 
661:	ILGEMESETA KVNIKGSIAY VAQQPWIMNT SLQQNILFGQ DLDKKKYEYI LDASALRKDL 
721:	EVLPGGDQTE IGEKGINLSG GQKQRVSLAR AVYQNADIYL LDDSLSAVDA HVGKHIFDKI 
781:	IGSNGLLKEK TRILVTHGLN FIRKVDIIIT MVDGQIGEIG SFDELTGHDG PFAGFMKTYM 
841:	AEELSTKDAQ NKDSYRTLEG IPTNDETMIH SSHSDIVHSI SDNSNIPIAR QMSRQTSCES 
901:	ESSEVLLHNN LVQEENTESV SVKLSVIMTY ARAVGFKVAL VILAINMVHE VAEMYLDVWL 
961:	SKWTQDHTNG TVNETQRNMR LGIYGAIGLF RGVSIFVTET FVTYGLIKAT RKLHRDLLRN 
1021:	ILRSPMSFFD TTPVGRIVNR FSKDIETIDD QLIYQFKDVV ICLFLVVCNT VVISTGTPHF 
1081:	LFIMLPVTVV YFALQRLYVS TSRQLRMMAS AARSPIFSHF GETISGCSTI RAFQQEERFM 
1141:	IESARRFDVL NTRRSLARSV EKWLHIRLDW LGSIIVLCVC LLVVVNKDDI SPGIVGLAIT 
1201:	YALNVTNCIE WLVKLTTNVG TNIISLERIK EYSETPTEAD WIVENKRPEH DWPNEGKVEM 
1261:	DNYGVRYREG LELVLKSISC KIAPCEKIGI VGRTGAGKSS LTMGLFRILE KAQGCIVIDG 
1321:	IDISTIGLHD LRSKITIIPQ DPVLFSGTMR MNLDPFDEYS NEDIWTALNH AHLKAFVIGL 
1381:	KDGLDHQCSE GGDNLSVGQR QLICLARALL RKTRILVLDE ATAAVDLETD DLIQTTIRTE 
1441:	FADCTILTIA HRLNTIMDYT RIMVLDCGQI REFDSPTNLL LDKNSIFYGM AKDAGLVS